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4 major brain regions
Cerebrum, diencehalon, brain stem, cerebellum
Gyri
Ridges
Sulci
Depression between ridges
Neuulation
Formation of nervous tissue, begins in 3rd week of embryonic development
Neural plate
Part of the embryoectoderm layer
Notochord
Beneath neural late. It induces the neural plate o form the neural tube, which develops in to the CNS
Neurulation event
Plate develops neural groove, neural groove deepens as folds rise and approach one another, neural crest cells separate from neural folds and form other structures, y the end of 3rd week folds meet and form real ube surrounding the neural canal
Neural crest cells
Tips of the neural folds
Neuropores
Openings of the neural tube. Cranial neuropore and caudal
Spina bífida
Failure to close caudal portion of neural tube
Anencephaly
Substantial or complete absence of a brain. infant dies
Primary brain vesicles
Form by late 4th week from cranial neural tube. Forebrain, midbrain, hindbrain
Prosencehalon
Forebrain
Mesencephalon
Midbrain
Rhombenvephalon
Hindbrain
Secondary brain vesicles
Form by 5th week. Telencephalon, diencephalon, mesecephalon, metencephalon, myelencephalon
Telencephalon
Becomes cerebrum
Diencephalon
Ecomes thalamus, hypothalamus epithalamus
Mesencephalon
Becomes midbrain
Metencephalon
Becomes pons ad cerebellum
Myelencephalon
Becomes mededulla oblongata
Gray matter
Made of neurocell bodies, dendrites and unmyelinated axons
Cortex
Superficial layer of gray matter
Nucleus (center)
Region of gray meter ( cluster of cell bodies) either lose to the surface or deep with the brain
White matter
Consists of myelinate axons and organized in uncles called tracts.
Peduncles
Tracts connecting two regions of the brain
Funiculi
Subdivision of tracts within spinal cord
Ganglia
A bunch a neuron cell bodies
Nerves
Bundles of axons
Nerve plexus
Network of of nerves
Brain protection
Bones of the skull, cranial meninges, cerebrospinal fluid, blood brain barrier
Cranial meninges
Has 3 connective tissue layers, separates and support soft tissue of brain, encloses and protect blood vessels supplying the rain help contain and circulate cerebrospinal fluid.
Pia matter
Innermost meninges; adhere to brain surfac thin ayer of areolar tissue
Arachnoid mater
Lies external to pia matter has arachnoid trabecuale and subarachnoid space made of web collagen and elastic fibers. Lied deep to dura mater
Dura mater
Pugh outer membrane. Made of dense irregular connective tissue in 2 layers : meningeal layer, periosteal layer
Memingeal layer
Deeper layer of dura
Periosteal layer
More superficial layer of ura that forms he periosteum on internal surfaces of cranial bones
Epidural space
Is potential space between dura and the skull. Contains arteries and veins
Dural venous sinuses
Areas in which eningeal layer and periosteal layer separate drain blood from the brain
Meningitis
Inflammation of the meninges, typically by viral infection. Ay result in brain damage or death if left untreated
Encephalitis
Inflammation of the brain
Epidural hematoma
Pool of blood in the epidural space of the brain
Subdural space
Potential space between dura mater and arachnoid mater
Subdural hematoma
Hermorrhage in subdural space. Compression of brain tissue occurs more slowly than epidural hematoma
Cranial dural septa
Sheets of dura mater hat extends into cranial cavity. Forms partitions between brain areas; provide support
Flax cerebri
Largest dural septa, located on midline, separates left nd right hemispheres of the cerebrum.conatins superior sagitario sinus and inferior agita al sinus
Tentorium cerebelli
Separates occipital and temporal lobes from cerebellum. Contains transverse sinuses withi posterior border, straight sinus along midsaggital plane. Has tenorial notch allowing room for brain stem
Falx cerebelli
Separates left and right sides of cerebellar emispheres ins along sagitario plane. Contains occipital sinus
Diaphragma sellae
Smallest of dural septa. Forms roof over sellica of sphenoid bone and pituitary gland
Dural venous sinuses
Modified vein that are rage, blood filled spaces that collect blood draining from brain. Usually triangular in section
Confluence of sinuses
Superior and inferior agitar sinuses, transverse sinuses straight sinus converge here
Ventricles
Cavities within the brain, lined ependymal cells, contain cerebrospinal fluid, connect with each other and with spinal cord central canal
Cerebrospinal fluid
Clear, colorless liquid surrounding CNS. Inculcates in vesicles and subarachnoid space. (Buoyancy) Reduces brains apparent weight by 95%, provides a liquid cushion (protection), transport of nutrients/ wastes and protects against fluctuations (environmentally stability)
Cerebrospinal fluid
Formed by choroid plexus in each ventricle. Blood plasma filtered from blood capillaries across both capillary walls and the pia mater its composition is modified by the ependymalell as it moves through these cells. Fluid is then released into ventricle and is referred to as CSF
Blood Brain barrier
Egulates which substances enter brain interstitial fluid, helps prevents neuron exposure to harmful substances(drugs wastes), composed of specialized capillaries reduced in certain locations for functional reasons (Ike choroid plexus needs to produce CSF)
Waste removal
Te-laden CSF drains into dural venous sinuses. Meningeal lymphatic vessels and glymphatic system
Meningeal lymphatic vessel
Located within meninges, absorb and transport excess fluid
Glyphatic system
Perivascular feet of atrocytes facilitate removal of waste
Cerebrum
Origin of all complex intellectual functions, two large cerebral hemispheres (each divided into lobes). Center of intelligence and reasoning, thought Emory, judgement, voluntary control of skeletal muscle, conscious perception of senses
Frontal lobe
Anterior part of cerebrum. Contains precentral gyrus, central sulcus, lateral sulcus. Functions: motor control, concentration, verbal communication, decision making, planning persionality.
Parietal lobe
Evaluating shape and texture
Temporal lobe
Hearing and smell
Occipital lobe
Visions and visual memories
Ínsula
Small lobe that can be observed by pulling away temporal lobe. Memory and sense of taste
Motor areas
Housed within frontal lobes. Primary motor cortex, motor speech area, frontal eye field, premotor cortex
Primary motor cortex
Located in presentar gyrus. Controls skeletal uscle activity
Aracnoid trabeculae
Extend to pia mater though subarachnoid space
Subarachnoid space
Contains cerebral fluid
Motor areas
Housed within frontal lobes. Mary motor cortex, motor speech area , rental eye field, pre motor cortex
Primary motor cortex
Located in precentral gyrus. Ontrol skeletal muscle activity on opposite side of body.
Motor speech area
Located in infrerolateral portion of frontal lobe. Controls movement for vocalization
Frontal eye field
Located on superior urface of middle frontal gyrus regulates eye movements needed for reading and binocular vision
Promotor cortex
Located anterior to precentral gyrus. Coordinates learned skilled activities
Primary somatosensory cortex
Located in post central gyrus of parietal lobes. Receives somatic information from proprioceptors, touch,pressure pain, temporal captors. Large regions for lips, fingers, genital regions
Somatosensory association area
Immediately posterior to postcentral gyrus. Integrates touch info allowing us to identify objects by feel
Primary visual cortex
Located within occipita lobe; receives processes, stores visual information
Secondary association area
Surrounds primary visual cortex. Integrates and interprets color, form, to allow identification recognition of things (like faces)
Primary auditory cortex
Located within temporal lobe. Receives processs stores auditory information
Auditory association area
Located temporal lobe; integrates and interprets sounds
Primary olafactory cortex
Located within temporal lobe. Receives processes and stores odor information
Primary gustatory cortex
Located within ínsula receives processes stores taste info
Functional brain regions
Integrate information from multiple association area
Prefrontal cortex
Located rostral to premotor cortex. Complex thought, judgement, personality, planning, deciding
Wernicke area
Typically located in left hemisphere, overlaps parietal and temporal beds. Involved n language comprehension
Central white matter
Lies deep to gray cerebral cortex. Composed of myelinated axons grouped into tracts.
Association tracts
Connects regions of cerebral cortex within same hemisphere. Arcuate fibers and longitudinal fasciculi
Arcuate fibers
Short tract connecting neighboring gyri
Longitudinal fasciculi
Longer tracts connecting gyri in different lobes
Commissural tracts
Connects region in different hemispheres
Projection tracts
Link cerebral cortex to inferior brain regions and spinal cord
Petalias
Protrusion of a lobe on one side compared to other side. Right handed individuals end to have right frontal petalis and left occipital petalis.
Cerebral lateralization
Two sides of cerebrum exhibit differences in higher order functions. (Certain functions are more dominant in one hemisphere than the other)
Categorical hemisphere
Is usually left hemisphere . Pecialized for language abilities, functions in categorization and analysis.contains wernicke and motor speech area
Representational hemisphere
Usually the right hemisphere. Concerned with visuospatial relationships, imagination, comparison of senses
Epilepsy
Neurological disorder. Neurons transmitting action potential too frequently and rapidly
Cerebrovascular
Reduced blood supply to part of brain due to blocked arterial blood vessel or hemohage
Cerebral nuclei
Paired masses of gray matter located deep within central white matter. Helps regulate motor output
Caudate nucleus
Enlarged head nd slender tail paralleling lateral ventricl
Lentiform nucleus
Rounded mass between ínsula and diencephalon. Composed of putame and globus
Putamen
Helps control movements at subconscious level.