TCA Cycle
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9 Terms
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Acetyl CoA Formation
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Step 1 - Citrate Synthase Reaction: Acetyl-CoA + Oxaloacetate + H2O→Citrate + CoA-SH
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Step 2 - Aconitase Reaction: Citrate→Isocitrate
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Step 3 - Isocitrate Dehydrogenase Reaction: Isocitrate + NAD+ →α-Ketoglutarate + CO2 + NADH + H+
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Step 4 - α-Ketoglutarate Dehydrogenase Reaction: α-Ketoglutarate + CoA-SH + NAD+ → Succinyl-CoA + CO2 + NADH+ H+
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Step 5 - Succinyl-CoA Synthetase Reaction: Succinyl-CoA + GDP + Pi→ Succinate + GTP + CoA-SH
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Step 6 - Succinate Dehydrogenase Reaction: Succinate + FAD → Fumarate + FADH2
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Step 7 - Fumarase Reaction: Fumarate+H2O→Malate
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Step 8 - Malate Dehydrogenase Reaction: Malate + NAD+ → Oxaloacetate + NADH+ H+
