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PTSD
-persistent psychological distress following exposure to actual or threatened death, serious injury, or sexual violence
-most do not seek treatment until 4.5 years after sx onset
PTSD patho
-failure of normal fear extinction
-hyperactive amygdala leads to exaggerated fear response
-sympathetic nervous system hyperactivity
-elevated norepinephrine contributes to hypervigilance and exaggerated startle, serotonin dysregulation affects mood and impulse control
PTSD risk factor
-exposure to actual or threatened death, serious injury or sexual violence
-intentional trauma have higher risk of developing PTSD
-combat exposure, sexual violence, childhood trauma
-MVA, natural disaster, medical trauma
Protective factors: resilience, positive coping, strong social support, prior positive life experience, higher socioeconomic resource, early intervention
PTSD sx
-marked cognitive, affective, or behavioral sx in response to reminder of traumatic event
-persist >1 month
-flashbacks, severe anxiety, dissociative episodes, fleeing or combative behavior
-unwanted intrusive memories, nightmares, flashbacks, psychologic distress
-can occur spontaneously or be triggers by event that resemble trauma
-avoidance of stimuli associated with event
-depression and negative mood
-irritability, aggressive physical or verbal behaviors
-headache, GI issue, chronic pain, muscle tension, fatigue
-anxious, hypervigilant, guarded, cant sit still
-asses for suicidal ideation/plan/intent -> up to 20% may attempt suicide
PTSD dx
DSM-5 Criteria
-must be exposed to traumatic event + sx from the following catagories for >1 month
- 1 Intrusion symptoms
- 1 Avoidance symptoms
- 2 Negative effects of cognition and mood
- 2 Altered arousal and reactivity
-Not better explained by something else
Screening
-PCL-5 -> 31-33 suggest PTSD
-Primary care PTSD screen
PTSD tx
Nonpharm
-first line = trauma focused psychotherapy
-sleep hygiene, exercise, stress management
Pharm
-first line = sertraline and paroxetine
-second line = fluoxetine
-prazosin -> help with nightmares
Acute Stress Disorder
-trauma and stressor related disorder characterized by intrusion, negative mood, dissociation, avoidance and arousal sx occuring 3 days - 1 month
-50-80% develop PTSD
Acute Stress Disorder patho
-failure of normal psychological and physiological recovery process in the immediate aftermath of trauma
Acute Stress Disorder etiology
-MVA
-physical assault
-serious accident, natural disaster
-life threatening medical events
Acute Stress Disorder sx
-temporal relation of sx to traumatic event must be present 3 days - 1 month
-intrusive sx, negative mood, dissociative sx, arousal sx
-hypervigilance, withdrawn affect, anxious or depressed mood
Acute Stress Disorder dx
DSM-5 Criteria
-must be exposed to traumatic event + 9 sx across the categories from 3 days - 1 month after exposure
- Intrusion symptoms
- Avoidance symptoms
- Negative effects of cognition and mood
- Altered arousal and reactivity
-Not better explained by something else
Screening
-ASDI, ASDS
Acute stress disorder tx
Nonpharm
-first line = trauma focused psychotherapy
-sleep hygiene, education
-safety planning, social support
adjustment disorder
-maladaptive emotional or behavioral responses to identifiable psychosocial stressor -> response is out of proportion to severity of stressor
-women
-15-25 year old
adjustment disorder patho
-failure of normal stress adaptation and coping mechanism rather than fundamental neurological dysfunction
adjustment disorder etiology
-occur within 3 months of stressor onset
-any type or severity
-can be a single or multiple event
-relationship issues
-occupational/academic concern
-financial issue
-loss
-developmental milestones
adjustment disorder sx
-sx develop within 3 months of onset of identifiable stressors and typically resolve within 6 months after stressor
-depressed mood, sadness, hopelessness
-crying spell, loss of enjoyment, irritability, anger
-decreased performance
-sx do not meet full criteria for another mental disorder
adjustment disorder dx
-only dx when criteria for other specific disorders are not met
-sx develop within 3 months of onset of identifiable stressors and typically resolve within 6 months consequence has ended
adjustment disorder tx
Nonpharm
-first line = psychotherapy or CBT
-stress management
grief and prolonged grief disorder
-higher risk: sudden death, child loss, violent death, poor social support, personal hx of depression
-symptoms persist >12 months
-significant function impairment
grief and prolonged grief disorder sx
-intense yearning/longing
-preoccupation with deceased
-identity disruption
-sense of meaningless
-intense emotional pain
-difficulty re-engaging with life
grief and prolonged grief disorder dx
DSM-5 Criteria
-loss of someone over one year ago
-persistent and pervasive grief response characterized by longing, yearning, and preoccupation with deceased
->3 of the following sx: identity disruption, disbelief, avoidance, intense emotional pain, difficulty reintegrating, emotional numbness, feeling like is meaningless, intense loneliness
grief and prolonged grief disorder tx
Nonpharm
-psychotherapy, psychoeducation, CBT