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The most obvious function of skeletal muscle is to _____
enable an individual to move freely and breathe
The innermost layer of connective tissue that surrounds individual muscle fibers is called
endomysium
Identify a true statement about the sarcolemma.
It surrounds the muscle fiber cell.
In response to resistance exercise training, _____ become activated and divide; this increases the number of nuclei in the muscle fiber
satellite cells
In order to maintain a constant myonuclear domain within skeletal muscle fibers, new nuclei are obtained and incorporated from ___
satellite cells
Identify the functions performed by skeletal muscles. (Select all that apply.)
Heat production during cold stress
Force generation for locomotion and breathing
Force generation for postural support
Within the sarcoplasm, there are numerous threadlike structures that contain contractile proteins. These are called ___
myofibrils
Match the layers of connective tissue (in the left column) with their locations in the skeletal muscle (in the right column).
Epimysium: It surrounds the entire muscle.
Perimysium: It surrounds individual bundles of muscle fibers.
Endomysium: It surrounds each muscle fiber within the fasciculus.
The cell membrane surrounding a muscle fiber cell is called the
sarcolemma
The two proteins located on the actin molecule that play an important role in the regulation of muscular contraction are ___
troponin and tropomyosin
Satellite cells play a key role in muscle growth and repair, because they are _____ cells
undifferentiated
The volume of cytoplasm surrounding an individual nucleus is termed the
myonuclear domain
The site where a motor neuron and a muscle cell meet is called the
neuromuscular junction
Myofibrils are composed of a thick protein filament and a thin protein filament called
myosin and actin
The sliding filament model of muscle contraction is also called the _____ of muscle contraction.
swinging lever-arm model
True or false: The majority of a muscle is made up of the proteins troponin and tropomyosin.
False. These proteins make up only a small portion of the muscle, but they play an important role in the regulation of the contractile process.
The energy for muscular contraction comes from the breakdown of adenosine triphosphate (ATP) by the enzyme
myosin ATPase
The pocket formed by the sarcolemma at the neuromuscular junction is called the
synaptic cleft
During the excitation process, depolarization of the muscle results in the
release of calcium from the sarcoplasmic reticulum
The process of muscular contraction is explained by the _____ model of contraction
sliding filament
is defined as a reduction in muscle power output that can result from a decrease in both muscle force generation and shortening velocity
Muscle fatigue
The breakdown of adenosine triphosphate and the release of energy serves to energize the
myosin cross-bridges
True or false: A potential cause of increased motor neuron excitability includes high levels of excitatory input to the motor neurons
True
Muscle fibers classified as type I and type II are also known as _____ fibers
slow twitch and fast twitch
In the excitation process, the binding of the neurotransmitter to receptors on the motor end plate leads to the
depolarization of the muscle cell
Identify factors that determine the oxidative capacity of a muscle fiber. (Select all that apply.)
The number of capillaries surrounding the fiber
The amount of myoglobin within the fiber
The number of mitochondria
Muscle fibers that have a high aerobic capacity will be fatigue resistant during
prolonged bouts of submaximal exercise
High-intensity exercise or prolonged, submaximal exercise results in a decline in the muscle's ability to generate power. This decrease is called
fatigue
Myosin isoforms influence muscle performance because they differ in
their myosin ATPase activity
Which of the following statements are true of exercise-induced muscle cramps
Experimental evidence suggests that exercise-induced muscle cramps can occur due to changes in the central nervous system.
Experimental evidence does not support the notion that dehydration is the most common cause of muscle cramps.
Human skeletal muscle can be divided into major classes based on the histochemical and biochemical characteristics of the individual fibers. These two general categories are _____ fibers.
type I and type II
Fibers that contain large amounts of actin and myosin
generate more force
The amount of myoglobin within a fiber influences its oxidative capacity because myoglobin
is similar to hemoglobin in that it binds oxygen
The contraction speed of muscle fibers is compared by measuring the maximal shortening velocity (called V max). V max is determined by the rate of
cross-bridge cycling
A muscle fiber with a high concentration of myoglobin, along with a high number of mitochondria and capillaries, will have a high _____ capacity
aerobic
Which of the following is true of muscle fibers with a high force generating capacity and a fast shortening velocity
They produce a high power output.
Muscle fibers that contain ATPase isoforms with high ATPase activity will degrade ATP rapidly and result in a high speed of
muscle shortening
The efficiency of a fiber is calculated by dividing the amount of energy used by the
amount of force produced
Identify the true statements about the difference between slow (type I) muscle fibers and fast (type II) muscle fibers. (Check all that apply.)
Slow (type I) muscle fibers have a higher resistance to fatigue than fast (type II) muscle fibers.
Slow (type I) muscle fibers have a larger capacity for aerobic metabolism than fast (type II) muscle fibers.
The contractile properties of muscle fibers are influenced by the
abundance of contractile proteins
Type II fibers have a limited capacity for aerobic metabolism because they
have a relatively smaller number of mitochondria
The key biochemical factor that regulates fiber V max is the
myosin ATPase activity
The maximal power output of a muscle fiber is defined as the product of force generation multiplied by the
shortening velocity
The fastest muscle fiber in human skeletal muscle is the _____ fiber.
type IIx
An efficient fiber would require _____ to perform a certain amount of work
less ATP
When compared to fast type II muscle fibers, slow type I muscle fibers, also known called slow-oxidative or slow-twitch fibers have
higher efficiency
Type II muscle fibers, also known as fast-twitch fibers are
rich in glycolytic enzymes
True or false: The term "muscle action" is now used to describe only shortening muscular contractions.
false
There is a quicker release of energy in fast fibers because of higher
ATPase activity
The myosin ATPase activity in type IIx fibers is higher than other fiber types, resulting in the highest _____ of all fiber types
V max
As the frequency of neural stimulation to a muscle is increased, the muscle does not have time to relax between stimuli, and the force produced is additive. This response of addition of successive twitches is called
Summation
The average sedentary man or woman possesses approximately _____ slow fibers
50%
At any absolute force the speed of movement is greater in muscles with a high percentage of _____ fibers
fast twitch
The term that has been proposed to describe the process of muscle force development is known as
muscle action
The speed of shortening is greater in fast fibers than in slow fibers, because the sarcoplasmic reticulum in fast fibers releases _____ at a faster rate
calcium ions
If the frequency of stimuli is increased past summation, individual contractions are blended in a single, sustained contraction called
tetanus
Match the type of athletes (in the left column) with their typical fiber make up (in the right column).
Power athletes: Large percentage of fast fibers
Endurance athletes: Large percentage of slow fibers
For both fast and slow fibers, the maximum velocity of shortening is greatest at the
lowest
True or false: The term "muscle action" is now used to describe only shortening muscular contractions
false