ADHD 2

what are some issues with classical medical treatments of ADHD?

class B drugs are being prescribed to children and this has significant abuse potential

there has been shown to be a link between distractibility and…

superior colliculus

the superior colliculus is the most important… and it has been shown that lesions in this area…

subcortical visual system, decrease distractibility

Goodale and Murison’s study on the superior colliculus found that..

lesioning of this area completely reduced the animals abilities to be distracted by a light

lesioning of the SC has led to a new theory that…

distractibility in ADHD reflects a hyperresponsive colliculus

the colliculus is involved in… integration, where… inputs converge into a common pool of neurons

multisensory, visual, auditory and somatosensory

amphetamine is able to…

turn off the colliculus for those with ADHD

Classical theories refers to ADHD as having something to do with… and the…

dopamine, dysfunction of the frontal cortex

the colliculus mediates distractibility but also regulates…

dopamine neurons

visual activation of dopamine neurons via input from the colliculus leads to… which is measured by…

dopamine release in the forebrain, amperometry

ADHD has also been thought to arise from… because the colliculus…

dysfunction of the cerebral cortex, receives from widespread areas of the cortex including the frontal cortex

the implications of identifying dopamine and colliculus as playing a role in ADHD are…

that it opens up new possibilities for drugs targeting colliculus and understanding underlying neural dysfunction