PoP II Exam 3 (Dr. Bennett)- GERD, Anti-emetic, IBS

H2 Receptor Agonist Medications

Cimetidine (Tagamet)

Famotidine (Pepcid, Pepcid AC, Zantac 360)

Nizatidine (Axid)

PPI Medications

Omeprazole (Prilosec, Prilosec OTC)

Omeprazole + Sodium Bicarbonate (Zegerid, Zegerid OTC)

Esomeprazole (Nexium, Nexium IV)

Lansoprazole (Prevacid)

Pantoprazole (Protonix, Protonix IV)

Dexlansoprazole (Dexilant)

Dopamine Receptor Antagonist Medications

Metoclopramide, domperidone, droperidol, haloperidol, chlorpromazine, prochlorperazine, promethazine, amisulpride

Mucosal Protectant Medications

Sucralfate (Carafate)

Misoprostol (Cytotec)

Bismuth Subsalicylate (Pepto Bismol, Kaopectate)

Opioid Agonist (Anti-diarrheal) Medication

Diphenoxylate + Atropine (Lomotil)

Loperamide (Imodium)

Eluxadoline (Viberzi)

5-HT3 Receptor Agonist Medication

Alosetron (Lotronex)

Ammonium Detoxicant (Laxative) Medication

Lactulose (Enulose, Kristalose, Constulose)

Osmotic Cathartic Medication

Polyethylene Glycol (Miralax)

Stool Softener Medication

Docusate Sodium (Colace)

Prostone Analog (laxative) Medication

Lubiprostone (Amitiza)

Guanyl Cyclase Agonist (Laxative) Medications

Linaclotide (Linzess)

Plecanatide (Trulance)

Antispasmodic (Anticholinergic) Medications

Dicyclomine (Bentyl)

Hyoscyamine (Levsin, Levbid, Anaspaz)

5-HT3 Receptor Antagonist Medications

Ondansetron (Zofran)

Granisetron (Kytril, Sancuso, Sustol)

Palonosetron (Aloxi)

Dolasetron

Antihistaminic/Anticholinergic Agent Medications

Promethazine (Phenergan)

Hyoscine (Scopalamine)

Diphenhydramine (Benadryl)

Dimenhydrinate (Dramamine)

Meclizine (Bonine, Antivert)

Substance P/NK-1 Receptor Antagonist Medications

Aprepitant or Fosaprepitant (Emend)

Rolapitant (Varubi)

Cimetidine Brand

Tagamet

Famotidine Brand

Pepcid, Pepcid AC, Zantac 360

Nizatidine Brand

Axid

Omeprazole Brand

Prilosec, Prilosec OTC

Omeprazole + Sodium Bicarbonate Brand

Zegerid, Zegerid OTC

Esomeprazole Brand

Nexium, Nexium IV

Lansoprazole Brand

Prevacid

Pantoprazole

Protonix, Protonix IV

Dexlansoprazole Brand

Dexilant

Sucralfate Brand

Carafate

Misoprostol Brand

Cytotec

Bismuth Subsalicylate

Pepto Bismol, Kaopectate

Diphenoxylate + Atropine Brand

Lomotil

Alosetron Brand

Lotronex

Lactulose Brand

Enulose, Kristalose, Constulose

Polyethylene Glycol Brand

Miralax

Docusate Sodium Brand

Colace

Lubiprostone Brand

Amitiza

Linaclotide Brand

Linzess

Dicyclomine Brand

Bentyl

Hyoscyamine Brand

Levsin, Levbid, Anaspaz

Granisetron Brand

Kytril, Sancuso, Sustol

Aprepitant or Fosaprepitant Brand

Emend

Rolapitant Brand

Varubi

Ondansetron Brand

Zofran

Palonosetron Brand

Aloxi

Metoclopramide Brand

Reglan

Promethazine Brand

Phenergan

Dolasetron Brand

Anzemet

Amisulpride Brand

Barhemsys

Hyoscine Brand

Scopalamine

Diphenhydramine Brand

Benadryl

Dimenhydrinate Brand

Dramamine

Meclizine Brand

Bonine, Antivert

Antihistaminic/Anticholinergic Antagonist ADRs

Drowsiness, anticholinergic effects, tachycardia

Amisulpride (Barhemsys) ADRs

QT prolongation, chills, hypokalemia, increase prolactin

Dopamine Antagonist ADRs

EPS/dystonia, sedative, hypotension, galactorrhea, breast tenderness, menstrual irregularities, acute EPS in children, decreased libido

Cannabinoid ADRs

Hallucinations, disorientation, vertigo, euphoria, depression, paranoia, tachycardia, hypotension

Cannabinoid Medications

Dronabinol (Marinol)

Nabilone (Casemet)

Benzodiazepine Medications

Midazolam, lorazepam

Benzodiazepine ADRs

Dependence, sedation, anterograde amnesia

Dexamethasone ADRs

Cushing’s syndrome, HTN, hyperglycemia

5-HT4 Receptor Agonist (Laxative) Medications

Tegaserod (Zelnorm)

Prucalopride (Motegrity)

Opioid Antagonist (Laxative) Medications

Methyl naltrexone (Relistor)

Alvimopan (Entereg)

Naloxegol (Movantik)

Alvimopan Brand

Entereg

Naloxegol Brand

Movantik

Methyl Naltrexone Brand

Relistor

Tegaserod Brand

Zelnorm

Prucalopride Brand

Motegrity

Eluxadoline ADRs

Constipation, nausea, increased LFTs, URI, increased risk of MI with long term use

Guanyl Cyclase Agonist ADRs

Diarrhea, don’t use in pediatrics cause serious dehydration