Summary of Reproductive Hormones

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30 Terms

1

Biochemical classification: neuropeptide (decapeptide)

Source: Hypothalamic surge and tonic centers

Male Target Tissue: Anterior lobe-pituitary (gonadotroph cells)

Gonadotropin releasing hormone (GnRH)

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2

Biochemical classification: glycoprotein

Source: anterior lobe (pituitary) (gonadotroph cells)

Male Target Tissue: testis (interstitial cells of Leydig)

Luteinizing Hormone (LH)

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3

Biochemical classification: glycoprotein

Source: anterior lobe-pituitary (gonadotroph cells)

Male Target Tissue: testis (sertoli cells)

follicle stimulating hormone (FSH)

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4

Biochemical classification: protein

Source: anterior lobe-pituitary (lactotroph cells)

Male Target Tissue: testis and brain

prolactin

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5

Biochemical classification: Neuropeptide (octapeptide)

Source: synthesized in the hypothalamus, stored in the posterior lobe-pituitary; synthesized by corpus luteum

Male Target Tissue: smooth muscle of epididymal tail, ductus deferens and ampulla

oxytocin (OT)

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6

Biochemical classification: steroid

Source: granulosal cells of follicle, placenta, Sertoli cells of testis

Male Target Tissue: brain, inhibits long bone growth

Estradiol (E2)

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7

Biochemical classification: Steroid

Source: Corpus luteum and placenta

Male Target Tissue:

progesterone (P)

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8

Biochemical classification: Steroid

Source: Interstitial cells of Leydig, cells of theca interna in female

Male Target Tissue: Accessory sex glands tunica dartos of scrotum, seminiferous epithelium, skeletal muscle

Testosterone (T)

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9

Biochemical classification: Glycoprotein

Source: Granulosal cells (female), Sertoli cells (male)

Male Target Tissue: Gonadotrophs of anterior lobe-pituitary

Inhibin

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10

Biochemical classification: Glycoprotein

Source: Placental cells (human female), granulosal cells (female), Sertoli cells (male)

Male Target Tissue: Gonadotrophs of anterior lobe-pituitary

Activin

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11

Biochemical classification: Prostaglandin (C-20 fatty acid)

Source: Uterine endometrium, vesicular glands

Male Target Tissue: Epididymis

Prostaglandin F2a (PGF2a)

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12

Biochemical classification: Prostaglandin (C-20 fatty acid)

Source: ovary, uterus, embryonic membranes

Male Target Tissue:

Prostaglandin E2 (PGE2)

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13

Biochemical classification: glycoprotein

Source: trophoblast of blastocyst (chorion)

Male Target Tissue:

human chorionic gonadotropin (hCG)

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14

Biochemical classification: Glycoprotein

Source: Chorionic girdle cells

Male Target Tissue:

equine chorionic gonadotropin (eCG)

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15

Biochemical classification: protein

Source: placenta

Male Target Tissue:

placental lactogen

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16

What female target tissue?

Male primary action: release of FSH and LH from anterior lobe-pituitary

Female primary action: release of FSH and LH from anterior lobe-pituitary

Anterior lobe-pituitary (gonadotroph cells)

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17

What female target tissue?

Male primary action: stimulates testosterone production

Female primary action stimulates ovulation, formation of corpora lutea and progesterone secretion

Ovary (cells of theca interna and luteal cells)

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18

What female target tissue?

Male primary action: Sertoli cell function

Female primary action: Follicular development and estradiol synthesis

Ovary (granulosal cells)

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19

What female target tissue?

Male primary action: can induce maternal behavior in females and males

Female primary action: lactation, maternal behavior and corpora lutea function (some species)

Mammary cells, corpus luteum in some species (rat and mouse)

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20

What female target tissue?

Male primary action: PGF2a synthesis and pre-ejaculatory movement of spermatozoa

Female primary action: uterine motility, promotes uterine PGF 2a synthesis, milk ejection

Myometrium and endometrium of uterus, myoepithelial cells of mammary gland

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21

What female target tissue?

Male primary action: sexual behavior

Female primary action: Sexual behavior, GnRH, elevated secretory activity of the entire tract, enhanced uterine motility

Hypothalamus, entire reproductive tract and mammary gland

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22

What female target tissue?

Male primary action:

Female primary action: Endometrial secretion, inhibits GnRH release, inhibits reproductive behavior, promotes maintenance of pregnancy

Uterine endometrium, mammary gland, myometrium, hypothalamus

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23

What female target tissue?

Male primary action: Anabolic growth, promotes spermatogenesis, promotes secretion of accessory sex glands

Female primary action: Substrate for E2 synthesis, abnormal masculinization (hair patterns, voice, behavior, etc.)

Brain, skeletal muscle, granulosal cells

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24

What female target tissue?

Male primary action: inhibits FSH secretion

Female primary action: inhibits FSH secretion

gonadotrophs of anterior lobe-pituitary

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25

What female target tissue?

Male primary action: stimulates FSH secretion

Female primary action: stimulates FSH secretion

Gonadotrophs of anterior lobe-pituitary

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26

What female target tissue?

Male primary action: Affects metabolic activity of spermatozoa, causes epididymal contractions

Female primary action: Luteolysis, promotes uterine tone and contraction, ovulation

Corpus luteum, uterine myometrium, ovulatory follicles

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27

What female target tissue?

Male primary action:

Female primary action: Ovulation, stimulates corpus luteum secretion of progesterone

corpus luteum, oviduct

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28

What female target tissue?

Male primary action: increase growth of fetal testis

Female primary action: facilitate production of progesterone by ovary

ovary

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29

What female target tissue?

Male primary action:

Female primary action: causes formation of accessory corpora lutea

ovary

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30

What female target tissue?

Male primary action:

Female primary action: mammary stimulation of dam

mammary gland of dam

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