Unit 10: Red Blood Cells

Blood

Connective Tissue

Splenomegaly

Enlargement of the Spleen

Spleen Functions

• filters blood

• removes old blood cells

• recycles iron

• makes WBCs

Blood Flow Through the Spleen

Receives 5-10% of cardiac output

2 Parts of Blood

1. Cells (formed) 45%

   • RBC (44%)

   • WBC (<1%)

   • Platelets (<1%)

2. Plasma (liquid) 55%

   • Water (92%)

   • Proteins

   • Amino Acids

Blood Volume

7-8% of Body Weight

Complete Blood Count

Centrifuge

Hematocrit

RBC %

Buffy Coat

• Made of WBCs and Platelets

• Separates RBCs and Plasma

Red Blood Cells

Erythrocytes

Iron

4 on Hb Protein used to transport Oxygen

Hemoglobin

Protein in RBCs

Shape

biconcave discs

Drop of Blood

5 million RBCs

Nucleus

NONE

Hematopoiesis

• formation of blood cells

• occurs in bone marrow

Erythropoietin

Hormone that increases RBC Production

Oxyhemoglobin

Light Red, full of Oxygen

Deoxyhemoglobin

Dark Red, low in Oxygen

Muscles to Heart

veins

Heart to Lungs

Oxygenation

Lungs to tissues

Arteries

Veins and Arteries Meet at Vessels

Capillaries

Cooleys Anemia / Beta Thalassemia

• 11th Chromosome

• affects RBCs

Hypochromia

low color of blood cells

Sickle Cell Disease

• genetic mutation

• skinny shaped cells

Most Common Blood Type (40%)

O

Rarest Blood Type (<1%)

AB-

Universal Donor (7%)

O-

Universal Recipient (4%)

AB+