Module 8 Disorders of the Upper GI Tract: Gastritis, GERD, PUD Pathophysiology & Pharmacology I

Flashcards covering key concepts related to gastric disorders, including definitions, classifications, and pharmacological treatments.

Gastritis

Inflammation of the stomach lining, which can be acute or chronic.

Acute Gastritis

Sudden mucosal inflammation often caused by NSAIDs, alcohol, stress, or bacterial toxins.

Chronic Gastritis

Progressive thinning of the stomach epithelium often caused by H. pylori or autoimmune conditions.

GERD (Gastroesophageal Reflux Disease)

Condition resulting from LES dysfunction leading to acid reflux, characterized by heartburn.

PUD (Peptic Ulcer Disease)

A condition where ulcers form in the stomach or duodenum due to erosion from gastric acid.

H. pylori

A bacterium associated with chronic gastritis and peptic ulcers.

Proton Pump Inhibitors (PPIs)

Medications used to reduce stomach acid production, common examples include omeprazole.

H2 Receptor Antagonists

Medications that block histamine H2 receptors to decrease stomach acid, such as famotidine.

Complications of Gastritis

Can include peptic ulcer disease, upper GI bleeding, pernicious anemia, and gastric carcinoma.

Clinical Red Flags for GI Bleeding

Symptoms such as hematemesis, melena, unexplained weight loss, and persistent vomiting.