Coagulation Studies

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week 1

Last updated 2:36 AM on 2/4/26
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9 Terms

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PT stands for:

Prothrombin time

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INR stands for:

International normalized ratio - standardizes the PT results

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PT/INR

Measures how long it takes for blood to clot - evaluates the extrinsic/common pathways, primarily for warfarin

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Prolonged PT/INR

Indicative of warfarin therapy, or liver disease

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D-Dimer

Protein fragment produced when a blood clot dissolves - fibrin degradation product

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Elevated D-Dimer implications:

Elevated in DVT (deep vein thrombosis), PE (pulmonary embolism), DIC (disseminated intravascular coagulation)

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aPTT stands for:

Activated Partial Thromboplastin Time

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aPTT function:

Blood test measuring how long it takes for blood to clot - evaluates intrinsic/common pathways, often for heparin

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Instances of prolonged aPTT

During heparin therapy, & hemophilia

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