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sexual reproduction
offspring gets genetic material from two different parents
gametes
specialized cells that can combine genes to form new individuals
sperm
what is the male gamete?
ovum
what is the female gamete?
haploid
an organism or cell having only one complete set of chromosomes.
primary sex organs
gonads, used to produce gametes
testes
what is the male primary sex organ?
ovaries
what is the female primary sex organ?
secondary sex organs
used to combine and nurture gametes
penis, prostate gland, seminal vesicles, ductus deferens, epididymis
what are the male secondary sex organs?
uterus, uterine tubes, vagina
what are the female secondary sex organs?
to store and move sperm
what is the purpose of the male secondary sex organs?
to move ovum and nurture embryo
what is the purpose of the female secondary sex organs?
secondary sex characteristics
external features that appear at puberty
pubic, axillary, and facial hair distribution, deeper voice, muscular build
what are the male secondary sex characteristics?
pubic hair, breasts, higher voices, wider pelvis
what are the female secondary sex characteristics?
sex determination
the biological mechanism that determines whether an organism will develop as a male or female
chromosomes
long sequences of DNA that contain genes
X and Y
what are the sex chromosomes?
male or female
what does the combination of sex chromosomes determine?
female default value
The concept that all human embryos begin with the same undifferentiated structures, and in the absence of a Y chromosome and SRY gene, they develop along the female pathway
female structures develop
what happens if no Y chromosome develops?
female structures degenerate + male structures develop
what happens if a Y chromosome develops?
XY
male sex chromosomes
XX
female sex chromosomes
sex determining region of the Y chromosome
SRY
SRY
makes TDF and triggers testes formation
testes determining factor
TDF
TDF
leads to preservation of male structures and secretion of anti-mullerian hormone
anti-mullerian hormone
a peptide secreted by the fetal testes that inhibits the development of uterus, uterine tubes, parts of vagina (degeneration of female structures)
morphologically female
what happens if TDF is absent or non-functional?
morphologically
refers to appearance
near the kidney
where do the testes develop?
7th week
around what week of development do testes begin to form?
inguinal canal into scrotum
what do the testes descend through?
around birth
when should the descent of testes be completed?
to keep them cool
why are testes kept outside the body cavity?
2
how many degrees below body temp should the testes be?
cryptorchidism
testes fail to descend
female designation, sterility
what can cryptorchidism lead to?
trisomy
3 copies of a chromosome, usually "embryonic lethal"
trisomy 21
leads to down syndrome
trisomy 18
edward's syndrome; causes low birth weight, heart defects, fatal by first year, though some live into 20s or 30s with significant mental handicaps
trisomy 13
causes severe organ and skeletal developmental issues, leads to a miscarriage, or is fatal within the first few days to a year
klinefelter syndrome
extra X chromosome; XXY or can even be XXXY
turner's syndrome
having only a single X chromosome; XO
atypical division during fetal development
what does turner's syndrome come from?
small/undescended testes, decreased testosterone + sperm production
what are the effects of klinefelter syndrome?
1:15000
what is the occurance of klinefelter syndrome?
low estrogen levels, secondary sex characteristics are not fully developed at puberty
what are some effects of turner's syndrome?
congenital adrenal hyperplasia
excessive cell growth in the adrenal glands
cortisol, aldosterone, androgens
what do the adrenal glands produce?
spermatozoa
a mature sperm cell
sustentacular (nurse) cells
- form blood-testes barrier
- support sperm development
- secrete fluids
epididymis
stores sperm and allows them to mature
seminiferous tubules
site of sperm production
follicle-stimulating hormone (FSH)
formed in the anterior pituitary and stimulates sperm production and follicles of ovary
inhibin
from nurse cells and inhibit sperm production
ductus deferens
carries sperm from epididymis to urethra
seminal vesicles
- 40% of the final volume
- slightly alkaline to buffer the acidic female reproductive tract
- uses fructose for energy
- activate flagella
prostaglandins
signaling molecules
signaling
what is the overall function of prostaglandin?
prostate gland
30% of volume and are clotting proteins with unknown function
bulbourethral gland
- secretions occur just prior to ejaculation
- alkaline to neutralize pH of male urethra
- provides some lubrication for intercourse
parasympathetic response
what type of response is erection?
sympathetic response
what type of response is emission?
emission
what happens when the bulbourethral gland secretions are released so that seminal fluid moves into the male urethra?
sympathetic
what type of response is ejaculation
ejaculation
-contractions of the bulbourethral muscle that surround the corpus spongiosum and contractions of ischiocavernosus muscle that surround the corpora cavernosa cause this
hormones from hypothalamus, anterior pituitary, and ovaries
what is the menstrual cycle controlled by?
28 days
around how long does the menstrual cycle take?
ovarian and uterine
what are the two main phases of the menstrual cycle?
pre-ovulatory (follicular) phase and post-ovulatory (luteal) phase
what are the 2 phases of the ovarian cycle?
follicular phase
The first phase of the ovarian cycle, during which a follicle (an oocyte and its surroudning cells) enlarges and matures and typically lasts from day 1 to day 14 of the menstrual cycle. The follicle secretes estrogen during this time period.
follicular-stimulating hormone
what hormone controls the follicular phase of the ovarian cycle?
1 year
how long does follicular development take?
luteal phase
corpus luteum secretes progesterone, which maintains endometrium and inhibits GnRH pulse frequency, which therefore inhibits FSH and LH
corpus luteum
what controls the luteal phase of the ovarian cycle?
luteinizing hormone (LH)
secreted by the pituitary gland to promote ovulation
progesterone
hormone that maintains the endometrium
GnRH pulse frequency
Changes in GnRH pulse frequency:
are controlled by estrogens and progestins
increase
estrogens ___________ pulse frequency
decrease
progestins ___________ pulse frequency
tipping point
when estrogen levels are high enough to cause a positive feedback loop instead of a negative feedback loop
proliferative phase and secretory phase
what are the two phases of the uterine cycle?
proliferative phase
- prepares the endometrium for implantation
- begins ~7 days after menses
- rising estrogen levels
- functional zone of the endometrium. thickens, secretes mucus, and increases vascularization
menses
menstrual cycle
secretory phase
endometrium secretes more mucus, which is maintained by progesterone from the corpus luteum
implantation of blastocyst
- corpus luteum is maintained
- progesterone levels stay elevated
- endometrium is maintained
no implantation of blastocyst
- corpus luteum degenerates after around 14 days
- progesterone is shut off
- endometrium is shed (menses begins)
erection
increased blood flow to the clitoris and greater vestibular gland
parasympathetic system
what system controls secretion of vestibule glands female?
secretion of vestibule glands
- provides lubrication for intercourse
- female secretion
climax
rhythmic contractions of smooth muscle around uterus and vagina
sympathetic system
what system controls the climax (female)
conception
needs to occur within 12-24 hours after fertilation
acrosomal enzymes
- kills and breaks apart granulosa cells
- dissolves zona pellucida
polyspermy
fertilization by more than one sperm
fast block
Na+ causes hardening of zona pellucida to prevent polyspermy
slow block
Ca2+ causes the removal of sperm receptors