Histamine (structures)

What structure is this?

Bropheniramine (Dimetapp)

[alkylamine]

1st generation antihistamine

What structure is this?

Cyproheptadine (periactin)

[piperidine]

1st generation antihistamine

What structure is this?

Diphenhydramine (benadryl)

[ethanolamine]

1st generation antihistamine

What structure is this?

Promethazine (phenergan)

[phenothiazine]

1st generation antihistamine

What structure is this?

Hydroxyzine (atarax)

[piperizine]

1st generation antihistamine

prodrug of cetirizine (zyrtec)

What structure is this?

Pyrilamine

[ethykebediamine]

1st generation antihistamine

What structure is this?

Azatadine

1st generation antihistamine

*not used this is the structure loratadine/desloratadine is based on

What structure is this?

Loratadine (Claritin)

2nd generation antihistamine

What structure is this?

Desloratadine (clarinex)

2nd generation antihistamine

What structure is this?

Fexofenadine (allegra)

2nd generation antihistamine

active metabolite of terfenidine (seldane)

What structure is this?

Cetirizine (zyrtec) OR levocetirizine (Xyzal)

2nd generation antihistamine(s)

cetirizine is active metabolite of hydroxyzine

What structure is this?

Terfenidine (seldane)

2nd generation antihistamine

prodrug for fexofenadine (allegra)

**no longer used due to HERG block

What drug is this?

Olopatadine (patanol)

Topical antihistamine (eye drops or nasal spray)

What drug is this?

Azelastine (astelin)

topical antihistamine (eye drop or nasal spray)

What drug is this?

Ketotifen (zaditor)

topical antihistamine (eye drops)

What drug is this?

Famotidine

H2 antagonist

What drug is this?

cimetidine

H2 antagonist

what drug is this?

nizatidine

H2 antagonist

what drug is this?

ranitidine

H2 antagonist

what drug is this?

fluticasone (flonase)

glucocorticoid

intranasal

What structure is this?

budesoide (Rhinocort)

glucocorticoid

intranasal