M06 ear drops

Otic preparations or Aural preparations

EAR DROPS aka

EAR DROPS

• Solutions of one or more active ingredients which exert a local effect in the ear:

• By softening ear wax, treating infection or inflammation

EAR DROPS

These are usually placed in the ear canal by drops or in small amounts for the removal of excessive cerumen (ear wax) for the treatment of ear infections, inflammation or pain.

Cerumen

combination of sweat and sebaceous gland of the internal auditory canal 

Carbamide peroxide

EARWAX-SOFTENING AGENTS INCLUDE

• twice a day for 4 days, and the ear canal may be irrigated with the use of an ear syringe

Carbamide peroxide should used

• To prevent vertigo, one should warm the vial of this medication in the hands and put 5-10 drops in the ear

Carbamide peroxide

Vertigo

• releases oxygen and via mechanical action of effervescence (formation of bubbles), loosens the wax debris and aids its removal

Action: Carbamide peroxide

(Debrox, Murine Ear)

only approved safe and effective for earwax removal.

• Do not use if ear drainage, discharge, pain or irritation or rash occurs

• Do not use if injury or perforation of the ear drums exists

If the patient feels pain or severe fullness in the ear when instilling drops in the ear, this might indicate the presence of aruptured tympanic membrane (damage/ripped ear drums)

CAUTIONS

olive oil, mineral oil , glycerin, diluted hydrogen peroxide (same MOA with Carbamide peroxide) solution, propylene glycol, baking soda solution

Other earwax softeners

(1/2 tsp sodium bicarbonate in 2 ounces of warm water)

baking soda solution

EAR CANDLE

• have gained popularity but not recommended.

• This is a hollow fabric cone impregnated with beeswax or paraffin and is about 1 foot long.

• triethanolamine polypeptide oleate (Cerumenex) may be used for impacted earwax. This is available for prescription

CERUMENOLYTIC ex

•  (arachis oil (peanut oil), turpentine and dichlorobenzene)

Cerumol

Sodium bicarbonate and glycerol

• Active ingredient, earwax softener

• Sodium bicarbonate 5 g

• Glycerol 30 mL

Water to 100 mL 15 ml

MASTER FORMULA FOR NaHCO3 EAR DROPS, BP

• For the softening and removal of earwax, usually prior to syringing with warm water

ACTION AND USES

• Based on 10-mL preparation 15Ml

• Weigh 500 780 mg sodium bicarbonate and dissolve in 6 mL water

• Carefully make up to 7 mL of water

• Carefully add glycerol up to 10 mL mark

• Pack in a 10-mL hexagonal amber, ribbed bottle with dropper 

• Polish and label the bottle on the three smooth sides

METHOD OF PREPARATION

• Shake well before use, and not to be taken. For external use only

• The bottle may be warmed in the hands before placing drops in the ear.

• A patient information leaflet should be used to describe how to use the drops

ADVICE AND LABELLING

• Amber, ribbed hexagonal glass bottle which is fitted with a rubber dropper

• Manufactured ear drops are usually packed in small glass or plastic containers with a dropper

CONTAINERS FOR AURAL PREPARATIONS