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Nervous system
=responsible for reception & processing of sensory information
->from both external & internal environments
2 major divisions
1) CNS (Central nervous system)
1. Brain (protected by skull), connected with:
2. Spinal cord (protected by vertebral column)
2) PNS (Peripheral nervous system)
=nerves/zenuwvezels (liggen buiten ZS)
->division CNS & PNS=arbitrary (work together & are connected to each other)
->sensoric/motoric
3 specific functions nervous system
1) Receiving sensory input (PNS)
>sensory receptors in skin & other organs
->respond to external/internal stimuli by generating nerve signals (travel via PNS to CNS)
2) CNS: information processing & integration
~summing up input it receives from all over the body
->reviews info, stores it & creates appropriate motor responses
3) CNS: generates motor output
->nerve signals travel via PNS to muscles, glands, organs…
Sensorische /afferente vezels
1. Somatisch (signalen van huid, spieren, zintuigen)
2. Visceraal (signalen van inwendige organen)
Motorische
/efferente vezels
1. Somatisch: vrijwillig
~signalen naar skeletspieren
2. Autonoom: ongecontroleerd
~signalen nr smooth muscle, hartspier, klieren
->sympatisch (fight/flight)
->parasympatisch (rest/digest)
2 types of cells
1. Neurons
~communication within NS via nerve impulses
2. Neuroglia (glial cells)
~support & nourish neurons
->outnumber neurons by many!
Types of neuroglia
1) Microglia
2) Astrocytes
3) Schwann cells
4) Oligodendrocytes
Microglia
=phagocytic cells: help remove bacteria & debris (fagocyten, verwijderen pathogenen & afval)
Astrocytes
=provide metabolic & structural support directly to neurons
Tightly spiraled neuroglia that form myelin sheaths
1. Schwann cells (in PNS)
->gaps between myelin=nodes of Ranvier
->1 schwann cell myeliniseert 1 deel van xon
2. Oligodendrocytes (in CNS)
->1 olig. myeliniseert 1 deel v/meerdere axonen
3 types of neurons
~classified according to function
1) Sensory neurons
2) Interneurons
3) Motor neurons
->neurons vary in appearance but all have cell body, dendrites & axon
Sensory neurons
~in PNS: takes signals from sensory receptors & transports them to CNS
->sensory receptors =special structures that detect changes in the environment
Interneuron
~in CNS: 1. Receive sensory input from sensory neurons (& other interneurons)
2. Sum up all information received
3. Communicate with motor neurons
Motor neurons
~take nerve impulses away from CNS to an effector
->effectors carry out responses to environmental changes (both external & internal)
Dendrites
=short extensions: receive signals from sensory receptors or other neurons
->incoming signals from dendrites can result in nerve signals (which are then conducted by an axon)
Axon
=part of neuron that conducts nerve impulses
->can be very long
->individual axons=nerve fibers (collectively they form a nerve)
->many axons are surrounded by myelin sheath
Carrying nerve signals
Sensory neurons
->very long axon carries nerve signals from dendrites (associated with a sensory receptor) to CNS
->this axon is interrupted by cell body
Inter- & motor neurons
->multiple dendrites take signals to cell body
->then axon conducts nerve signals away from soma
Myelin sheath
=membranes of schwann cells (PNS) or oligodendrocytes (CNS) that are wrapped around an axon many times
->long axons usually have myelin sheath (short axons don’t)
Functions of myelin sheaths
1. Nodes of Ranvier =gasps with no myelin sheath
2. Important role in speed of transmission (rate at which signals move through neuron)
3. Important role in nerve generation in PNS (zenuwen herstellen)
->if axon is severed: myelin sheath remains & serves as a passageway for new fiber growth (nieuwe vezels)
4. Aandoening multiple sclerose: afbraak myeline (te veel)
Colours of matter
Gray matter in CNS: gray because contains no myelinated axons
<->white matter (does have)
<->PNS: myelin gives nerve fibers white appearance + serves as excellent insulator