Anirudh Mohanty - Honors Meiosis Notes
Purpose of meiosis:
To make gametes (egg and sperm cells)
Only body cells go through meiosis
Daughter cells have half the amount of DNA
Chromosomes:
Each person has 1 chromosome set from mom and 1 set from dad
Egg/sperm cells need only 1 set each
End result of meiosis:
Meiosis ends with genetically different cells
You resemble your siblings but are not identical to them
Phases of meiosis:
Interphase: Growth and DNA duplication
Prophase I: Nuclear membrane breaks down, chromosomes find their homologous pair, crossing-over can occur
Metaphase I: Homologous chromosomes line up in the middle, spindle fibers attach to the center of each chromosome
Anaphase I: Homologous pairs get pulled to opposite poles, separate the homologous pairs from each other
Telophase I / Cytokinesis: Nuclear membrane reforms, cells separate into two, only have half the number of chromosomes it started with
Prophase II: Nuclear membrane breakdowns in each cell, centrioles and spindle fibers reform
Metaphase II: Chromosomes line up in the middle, spindle attaches to centromeres
Anaphase II: Sister chromatids separate
Telophase II / Cytokinesis: Nuclear membrane reforms, cell divides and separates into four cells
End results of meiosis:
Cells at the end of meiosis are not identical
Centrosome, Interphase, chromosome, Prophase I, X, Recombination, Metaphase I, Anaphase I, Telophase I & Cytokinesis, Prophase II, Metaphase II, Anaphase II, Telophase II & Cytokinesis, Four granddaughter cells, n - haploid, 2n - diploid
Mitosis:
Purpose: Grow and repair cells
Ending cells: 2 identical, diploid cells
Meiosis:
Purpose: Make gametes
Ending cells: 4 non-identical, haploid cells
Centrosome, Interphase, chromosome, 2n, DNA is copied, Prophase I, X, Recombination occurs, Metaphase I, Chromosomes line up at equator, meiotic spindle, Anaphase I, Chromosomes pulled apart, Telophase I & Cytokinesis, Cell pinches in the middle, Prophase II, Two daughter cells, Metaphase II, Chromosomes line up at equator, Anaphase II, Sister chromatids pulled apart, Telophase II & Cytokinesis, Cell pinches in the middle, Four granddaughter cells, n - haploid, 2n - diploid
Mitosis:
Purpose: Grow and repair cells
Ending cells: 2 identical, diploid cells
Meiosis:
Purpose: Make gametes
Ending cells: 4 non-identical, haploid cells
Homologous Chromosomes:
Pair of maternal and paternal chromosomes that are similar in shape and size
Carry genes controlling the same inherited traits
Chromosome Number Errors:
Monosomy: Having one copy of a chromosome instead of two
Trisomy: Having three copies of a chromosome instead of two
Polyploidy: Having multiple copies of multiple chromosomes
Centromere Position:
Metacentric: Middle of the chromosome
Submetacentric: Between the center and end of the chromosome
Acrocentric: Near the end of the chromosome
Karyotypes:
Image of chromosomes from a diploid cell in which they are counted and matched
Distinguished by chromosome length, centromere position, and banding pattern
Nondisjunction:
When a pair of homologous chromosomes have failed to separate at anaphase
Results in both chromosomes of the pair passing to the same daughter cell
Chromosome structure errors:
Deletion: Part of a chromosome breaks off and attaches to a different chromosome
Inversion: Section of a chromosome breaks off and reattaches upside-down on the same chromosome
Duplication: Section of a chromosome is repeated
Chromosomal Disorders:
Down Syndrome: Also called trisomy 21, caused by an extra copy of chromosome 21, symptoms include intellectual disability and characteristic facial features
Patau Syndrome: Also called trisomy 13, caused by an extra copy of chromosome 13, symptoms include severe intellectual disability and physical abnormalities
Translocation, Inversion, deletions, duplication
Klinefelter Syndrome: where boys are born with an extra X chromosome
Purpose of meiosis:
To make gametes (egg and sperm cells)
Only body cells go through meiosis
Daughter cells have half the amount of DNA
Chromosomes:
Each person has 1 chromosome set from mom and 1 set from dad
Egg/sperm cells need only 1 set each
End result of meiosis:
Meiosis ends with genetically different cells
You resemble your siblings but are not identical to them
Phases of meiosis:
Interphase: Growth and DNA duplication
Prophase I: Nuclear membrane breaks down, chromosomes find their homologous pair, crossing-over can occur
Metaphase I: Homologous chromosomes line up in the middle, spindle fibers attach to the center of each chromosome
Anaphase I: Homologous pairs get pulled to opposite poles, separate the homologous pairs from each other
Telophase I / Cytokinesis: Nuclear membrane reforms, cells separate into two, only have half the number of chromosomes it started with
Prophase II: Nuclear membrane breakdowns in each cell, centrioles and spindle fibers reform
Metaphase II: Chromosomes line up in the middle, spindle attaches to centromeres
Anaphase II: Sister chromatids separate
Telophase II / Cytokinesis: Nuclear membrane reforms, cell divides and separates into four cells
End results of meiosis:
Cells at the end of meiosis are not identical
Centrosome, Interphase, chromosome, Prophase I, X, Recombination, Metaphase I, Anaphase I, Telophase I & Cytokinesis, Prophase II, Metaphase II, Anaphase II, Telophase II & Cytokinesis, Four granddaughter cells, n - haploid, 2n - diploid
Mitosis:
Purpose: Grow and repair cells
Ending cells: 2 identical, diploid cells
Meiosis:
Purpose: Make gametes
Ending cells: 4 non-identical, haploid cells
Centrosome, Interphase, chromosome, 2n, DNA is copied, Prophase I, X, Recombination occurs, Metaphase I, Chromosomes line up at equator, meiotic spindle, Anaphase I, Chromosomes pulled apart, Telophase I & Cytokinesis, Cell pinches in the middle, Prophase II, Two daughter cells, Metaphase II, Chromosomes line up at equator, Anaphase II, Sister chromatids pulled apart, Telophase II & Cytokinesis, Cell pinches in the middle, Four granddaughter cells, n - haploid, 2n - diploid
Mitosis:
Purpose: Grow and repair cells
Ending cells: 2 identical, diploid cells
Meiosis:
Purpose: Make gametes
Ending cells: 4 non-identical, haploid cells
Homologous Chromosomes:
Pair of maternal and paternal chromosomes that are similar in shape and size
Carry genes controlling the same inherited traits
Chromosome Number Errors:
Monosomy: Having one copy of a chromosome instead of two
Trisomy: Having three copies of a chromosome instead of two
Polyploidy: Having multiple copies of multiple chromosomes
Centromere Position:
Metacentric: Middle of the chromosome
Submetacentric: Between the center and end of the chromosome
Acrocentric: Near the end of the chromosome
Karyotypes:
Image of chromosomes from a diploid cell in which they are counted and matched
Distinguished by chromosome length, centromere position, and banding pattern
Nondisjunction:
When a pair of homologous chromosomes have failed to separate at anaphase
Results in both chromosomes of the pair passing to the same daughter cell
Chromosome structure errors:
Deletion: Part of a chromosome breaks off and attaches to a different chromosome
Inversion: Section of a chromosome breaks off and reattaches upside-down on the same chromosome
Duplication: Section of a chromosome is repeated
Chromosomal Disorders:
Down Syndrome: Also called trisomy 21, caused by an extra copy of chromosome 21, symptoms include intellectual disability and characteristic facial features
Patau Syndrome: Also called trisomy 13, caused by an extra copy of chromosome 13, symptoms include severe intellectual disability and physical abnormalities
Translocation, Inversion, deletions, duplication
Klinefelter Syndrome: where boys are born with an extra X chromosome