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why are cells small?
more efficient: surface area to volume ratio
how do cells stay small while the organism grows?
division
where does asexual reproduction occur?
in single celled organisms (bacteria, some simple animals/plants)
What is asexual reproduction?
The production of genetically identical offspring from a single parent
What is sexual reproduction?
Reproduction involving 2 parent organisms combining genetic material to create diverse offspring.
what are the advantages of sexual reproduction?
genetic diversity
why do cells divide?
growth, repair, reproduction
prokaryotic divison
binary fission
eukaryotic division
mitosis and meiosis
Prokaryote chromosome structure
single circular chromosome
eukaryotic chromosome structure
multiple and linear
histones
supporting proteins that help organize DNA
nucleosomes
DNA coiled around histones
How many chromosomes do humans have?
46
what is mitosis for
cell growth and repair
interphase
g1, s, g2
G1 phase
Cell growth
S phase
DNA replication (synthesis)
G2 phase
prepares for mitosis
M phase
mitosis and cytokinesis
phases of mitosis
prophase, metaphase, anaphase, telophase
what happens during prophase
chromosomes condense, nuclear envelope disappears, spindle forms
what happens during metaphase
Chromosomes line up in the middle of the cell
what happens during anaphase
sister chromatids separate and move along spindle fibers to opposite ends of the cell
what happens during telophase
spindle disappears, nuclear envelope forms
what happens during cytokenesis
cytoplasm divides; 2 new daughter cells
products of mitosis
two identical daughter cells (somatic cells)
Where is the G1 checkpoint?
end of G1
what happens at the G1 checkpoint
cells enter G0 unless there is a signal to divide (growth factor)
Where is the G2 checkpoint?
At the end of the G2 phase, before the start of the mitotic phase
what happens at the G2 checkpoint
The cell checks that the DNA has replicated, then enters M phase if MPF is present
Where is the M checkpoint
between metaphase and anaphase
what happens at the M checkpoint
cells enter anaphase when all chromosomes are attached to the spindle
what are cyclins
proteins that regulate the cell cycle
when are cyclins produced
during G2 phase
what is cdk
cyclin dependent kinase
where is cdk present
throughout the whole cell cycle
what is MPF
combination of cdk and cyclin
what does MPF do
triggers a cell's passage past the G2 checkpoint into the M phase (starts mitosis)
what is cancer
uncontrolled cell growth
what is meiosis
cell division that produces gametes for sexual reproduction
what does meiosis result in
4 haploid cells
what is the goal of crossing over
genetic diversity
what happens in prophase I
same as prophase, homologous pairs form tetrads, crossing over
what happens in metaphase I
Paired homologous chromosomes line up across the center of the cell
what happens in anaphase I
Homologous chromosomes separate, sister chromatids stay together
what happens in telophase I
2 nuclear envelopes form, chromosomes decondense, spindle disassembles
what happens in meiosis II
similar to mitosis (sister chromatids separate)
what is the end result of meiosis 2
4 haploid cells
what is the difference between male gametogenesis and female gametogenesis
male = 4 sperm cells, female = 1 large egg cell (unequal division of cytoplasm)
what are gametes
reproductive cells (sperm and egg)
what are gonads
organisms that produce gametes (ovaries and testes)
what is the sexual reproduction process
1. produce gametes, 2. gametes fuse to form zygote, 3. zygote undergoes mitosis and develops into a baby
testes
produces sperm and testosterone
scrotum
holds testes away from body to reduce temperature
Epididymis
location where sperm mature
vas deferens
tube that carries sperm from the epididymis to the urethra
prostate gland
A gland in males that contributes to the seminal fluid.
ovaries
produce egg cells and estrogen
fallopian tubes
where fertilization takes place, connects ovaries to uterus
uterus
supports growth and development of a fetus
cervix
The opening to the uterus
vagina
connects the uterus to the outside of the body
what do FSH and LH do
stimulate the gonads to produce sex hormones
where are FSH and LH produced
from the brain
steps of fertilization
1. sperm and egg meet in fallopian tube, forming a zygote 2. zygote is a diploid that goes through mitosis 3. embryo forms
what is an embryo
small ball of rapidly dividing cells
what is the placenta
connects maternal and fetal systems
where does the fetus develop
in the uterus
what happens during the first trimester
most dramatic change, body takes shape and organs form
what happens during the second trimester
growth and definement
what happens during the third trimester
period of primary growth