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spontaneous generation
the mistaken idea that living things arise from nonliving sources
Spontaneous Generation Theory
Decaying matter and mould generated bacteria
Contagionists
Believed disease could spread through contact
Anticontagionists
Believed disease spread through miasma
Miasma
bad air
What did Louis Pasteur do?
disprove spontaneous generation
What did Pasteur observe under the microscope
Unwanted microbes in wine and vinegar cells which turned liquids bad
When was germ theory published by Pasteur ?
1861
What did Pasteur show in Germ theory ?
Sterilised water was still sterile if the flask was closed but wasn't sterile if the flask was open
What did germ theory suggest
Germs were in the air
What else did Pasteur show with germ theory
Clean air from the countryside didn't carry bacteria but dirt air in city did
What did Pasteur do in 1878
Publish the germ theory of infection
What was germ theory
Germs causes decay
Who opposed germ theory
Dr Henry bastian
What was a flaw or Pasteur's theories
His research focused on how liquids like milk went sour so many didn't see the connection to humans
What theory did germ theory replace
Miasma theory
What did germ theory prove to wrong
Miasma theory , spontaneous generation , four humours theory
What long term effect did Pasteur cause
Cleanser hospitals , safer medical treatment , more vaccinations , survival rate in surgery
Who developed on Pasteur's work and applied it to humans
Robert Koch
What did Koch discover?
not all germs were the same
What did Koch discover 1882
Bacteria caused tuberculosis and a specific different microbe is present in every disease
What did Koch discover in 1883 and prove in 1884
Cholera was spread in water supplies
Who gave lectures on germ theory to British doctors opposing dr Henry bastian in the uk
John Tyndall
When did Tyndall give a lecture on germ theory
January 1870
Why did many people continue to believe in spontaneous generation in the uk
Bastian continued to believe this and he was so well respected so few people disagreed with him
What did koch begin
Bacteriology by developing the method of culturing bacteria in petridish with agar jelly )
What did Pasteur accidentally show in 1879
Vaccinations could prevent disease
What did Joseph Lister do?
Applied germ theory and linked it to infection by using antiseptic
Public health act 1848
To improve street cleanliness
Public Health Act of 1875
Mandatory for clean water ,proper sewage systems , rubbish on streets collected , appoint a medical officer of health
Second Reform Act (1867)
Gave the vote to more working class men
Great Stink (1858)
Stink of the Thames was so bad due to sewage and heat
Which engineer built a new sewer system of london (over 1300 miles of sewers )
Joseph bazalgette
What did Dr. Snow do?
Found what was causing cholera (it was the dirty water)He used spatial mapping
What helped dr snow
William Farr's statistics to see the link between cholera and dirty water
Where did most people live near in the cholera epidemic in 1854
The Broad Street water pump
What were the problems surgeons faced
Bleeding , infection , pain
Humphrey Davy (1795)
Nitrous oxide to numb pain with in dental surgery
Robert Liston
Used ether in an amputation in 1846- when amputating a leg
What did James Simpson do
Discovered chloroform 1847
Problem of chloroform
Had to be controlled doses (Hannah greener died from toe infection overdose 14year old )
Who used chloroform during childbirth in 1853, adding to its popularity?
Queen Victoria
What did Lister do?
created sterilization techniques to avoid infection (surgery room)
What did lister do 1865
Covered a wound of a patient with a bandage soaked in carbolic acid
When did lister publish the results of Jamie greenlees leg to publish in the medical journal 'lancet'
1867
Death rate change in lister patients
46% to 15%
Long term changes of antiseptics
Surgery went from antiseptic to aseptic
What did surgeons do now
Wore face masks surgical gowns and rubber gloves
What happened to surgical instruments
Steam sterilised
What happened to operating theatres to reduce infection
Decreased in size
Opposition towards anaesthetics and antiseptics
Initially increased death rate , pain was relief from god , many thought more likely to die if unconscious and still didn't understand germs
What did Florence Nightingale do?
Worked in the Crimean war in 1853 with 38 other nurses chosen by her to improve hygiene in hospitals
What book did Florence nightingale publish
Notes on nursing
How many wounded soldiers did Florence nightingale and co treat
2000
What did Florence nightingale reduce the mortality rate to
40% to 2%
What was set up in 1800
London college of surgeons
How much people died of smallpox 1796
3500
Inoculation (popular with aristocrats )
Putting pus from a mild form of smallpox
How much money did dr dimsdale make from inoculation
£10000
Edward Jenner theory
The milkmaid didn't get smallpox but caught mild case of cowpox (the 2 must be linked )
How did Jenner test his theory?(1796)
Infected an 8 year old boy (james Phipps ) with cowpox and then he didn't catch smallpox
When did Jenner publish his findings?
1798
Opposition to vaccination
The church thought it was against God's will and many doctors profited from inoculation as well as scientists in royal society disagreeing
Why did vaccination have a breakthrough
Parliament favoured it and in 1837 lancet blamed inoculation for smallpox outbreak so in 1840 inoculation was a crime
What happened in 1852 to then be enforced by the government in 1872
Vaccinations were made compulsory
Anti Jenner propaganda
Anti compulsory vaccination league in 1866
the royal jennerian society (vaccinated 12000 people in first 2 years
1803
Edwin Chadwick's Report
1842 ("Report on the Sanitary Conditions of the Labouring Population")
Laissez-faire
a policy or attitude of letting things take their own course, without interfering.
What was set up in 1800
London college of surgeons