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What is the scientific method?
A systematic process involving observation, hypothesis, experimentation, analysis, and conclusion
What is a hypothesis?
A testable and falsifiable explanation for an observation
What is a scientific theory?
A broad explanation supported by extensive evidence and widely accepted by scientists
What is basic science?
Science that expands knowledge without immediate application
What is applied science?
Science that solves real-world problems
What is biology?
The study of living organisms
What is homeostasis?
Maintaining stable internal conditions
What is evolution?
Change in allele frequencies in a population over time
What does “Order” mean in characteristics of life?
Organisms have organized structures such as cells
How do organisms respond to stimuli?
They react to environmental changes
What is reproduction in living organisms?
Producing offspring
What is growth and development?
Growing according to genetic instructions
What is energy processing?
Using energy for metabolism
What is homeostasis in living organisms?
Maintaining internal balance
What is evolutionary adaptation?
Population-level changes that improve survival
What is the Cell Theory?
All living things are made of cells; cells are the basic unit of life; all cells come from preexisting cells
What is the structure of a virus?
Genetic material inside a protein capsid, sometimes with an envelope
How do viruses replicate?
They attach, enter, replicate, assemble, and exit host cells
What components are found in all cells?
Membrane, cytoplasm, DNA, and ribosomes
What is a tissue?
A group of specialized cells working together
What is a colony?
Independent cells living together
What is a population?
Members of the same species in an area
What is a community?
All living organisms in an area
What is an ecosystem?
Living organisms plus the nonliving environment
What is the biosphere?
All ecosystems on Earth
What is taxonomy?
Classifying organisms by shared traits
What does biotic mean?
Living components of an ecosystem
What does abiotic mean?
Nonliving components of an ecosystem
What are prokaryotes?
Cells without a nucleus or membrane-bound organelles
What are eukaryotes?
Cells with a nucleus and membrane-bound organelles
Which cell type is oldest?
Prokaryotes
What is Domain Bacteria?
Domain of prokaryotes
What is Domain Archaea?
Domain of prokaryotes
What is Domain Eukarya?
Domain of eukaryotes
What do ribosomes do?
Make proteins
What does the nucleus do?
Stores DNA
What do mitochondria do?
Produce ATP
What do chloroplasts do?
Perform photosynthesis
What is a microbe?
A microscopic organism
What is an epidemic?
A disease outbreak in one region
What is a pandemic?
A disease outbreak that spreads globally
What is an antibiotic?
A substance that kills bacteria
What does an epidemiologist do?
Studies disease patterns and spread
What is a communicable disease?
A disease that spreads person to person
What is a non-communicable disease?
A disease that does not spread between individuals
What is antibiotic resistance?
When bacteria evolve traits that let them survive antibiotics
Which population evolves antibiotic resistance?
Bacteria, not humans
What is the Human Microbiome Project?
A project mapping microbes living on and in humans
How do microbes benefit humans?
They aid digestion, immunity, and protect against pathogens
How does breastfeeding affect a baby’s microbiome?
Provides beneficial microbes and antibodies
What happened when mice microbiomes were changed?
Their behavior, weight, and immunity changed
How do gut microbes help digestion?
They break down food and extract nutrients
How do gut microbes support immunity?
They train and regulate the immune system
What is the gut–brain axis?
Interaction between gut microbes and brain function
What is a pathogen?
A disease-causing organism
What is a host?
The organism a pathogen infects
What is an antigen?
A molecule that triggers an immune response
What is an antibody?
A protein that binds antigens
What is a macrophage?
A phagocyte that engulfs pathogens
What is an antigen-presenting cell?
A cell that displays antigens to activate T cells
What is a leukocyte?
A white blood cell
What are physical barriers to infection?
Skin, mucus, and other protective surfaces
What are chemical barriers to infection?
Stomach acid, enzymes, antimicrobial chemicals
What is innate immunity?
Fast, non-specific immunity
What is adaptive immunity?
Slow, specific immunity with memory
How do vaccines work?
They introduce antigens to produce antibodies and memory cells
What is autoimmunity?
When the immune system attacks the body’s own tissues
How does coronavirus enter cells?
Its spike protein binds to ACE2 receptors
What is the coronavirus spike protein?
The protein that binds to host ACE2 receptors
What genetic material do coronaviruses have?
RNA
What is an allele?
A version of a gene
What is a phenotype?
Physical expression of a trait
What is a genotype?
Genetic makeup of an organism, set of alleles that determine a trait
What is an adaptation?
A trait that increases survival or reproduction
What is a vestigial structure?
A reduced structure with little or no function
What is speciation?
Formation of new species
Who described natural selection?
Darwin and Wallace
What is Darwin’s principle of variation?
Individuals differ within populations
What is Darwin’s principle of inheritance?
Traits are passed from parents to offspring
What is Darwin’s principle of overproduction?
More offspring are produced than resources allow
What are the sources of genetic diversity?
Mutation and sexual reproduction
What evidence supports evolution?
Fossils, DNA, anatomy, biogeography, observed evolution
How did XBB evolve?
Through recombination and mutation
How did spike protein mutations affect XBB?
Improved immune evasion and ACE2 binding
What does the F486P mutation do?
Increases XBB.1.5 transmissibility
How does vaccination slow viral evolution?
Reduces spread and mutation opportunities
What is XBB?
A recombinant family of Covid‑19 subvariants
What is a T cell?
A lymphocyte that helps regulate and carry out adaptive immunity
What are elephant tusks?
Overgrown upper lateral incisors
Why are some African elephants tuskless?
Poaching selected for tuskless females who survived and reproduced
What genetic factor may cause tusklessness?
Mutations in tooth‑development genes such as wnt10a
What does “conserved” mean in evolution?
A trait that remains unchanged because it is essential
What is the relationship between teeth and tusks?
Tusks are modified teeth
How can tusk size affect survival?
Large tusks attract poachers; small or absent tusks increase survival
How can tusklessness evolve over time?
Individuals without tusks survive poaching and pass on the trait
Who are the Bajau people?
A Southeast Asian group known for extreme free‑diving
What physical adaptation do the Bajau have?
Enlarged spleens
How does a larger spleen help diving?
It releases extra oxygenated red blood cells during breath‑holding