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gametes
sperm and egg cells
what is meiosis
nuclear division that leads to halving of chromosome number in gametes to become haploids
homologs/ homologous chromosomes
similar in size and structure, contain same traits but not same DNA, carry different alleles of gene, on mom one dad
autosomes
numbered chromosomes in karyotype
what are germ cells
produce gametes during meiosis
what does meiosis do
DNA replicates once, then the DNA/ nucleus content divides twice
prophase 1
chromosomes pairs with homologous pair and crossover occurs
metaphase 1
homologous pairs line up in middle of cell, microtubules connect to kinetochore
anaphase 1
homologous pairs separate to opposite sides of cell, the sister chromatids remain together
telophase 1
nuclear envelope forms, spindle fibers disappear, chromosomes decondense
cytokinesis 1
cell separates into two cells
prophase 2
spindle fibers form, consists of chromosomes (two chromatids)
metaphase 2
chromosomes line up in the middle
anaphase 2
sister chromatids separate and move to opposite sides
telophase 2
chromosomes fully on opposite sends, nuclei form, chromosomes decondense, spindle fibers disappear
cytokinesis 2
cell seperates, now 4 cells
nondisjunction
failure of chromosomes to properly separate
what does nondisjunction cause
abnormal number of a specific chromosome
aneuploidy is what
wrong number of specific chromosomes
when does nondisjunction occur
anaphase 1 or 2
mendel’s 1st law
two versions of each gene (alleles)
monohybrid cross
crossing of two heterozygous individuals
mendel’s 2nd law
law of independent assortment, segregation of alleles for one gene does not influence segregation of other alleles
when do mendel’s laws not apply for single genes
incomplete dominance, codominance, pleiotropy
pleiotropy
gene mutation that causes multiple effects on phenotype
when do mendel’s laws not apply to two or more genes
epistasis and polygenic inheritance
what is epistasis
one genes masks the phenotypic expression of another gene