Childhood sepsis NOT DONE

What are the different types of shock?

Cardiogenic

Hypovolemic

Obstructive

Distributive: Septic, anyphalaxis

Pathophysiology of cardiogenic shock

myocardial damage → obstruction of outflow → Pump Failure

Pathophysiology of hypovelmic shock

Pathophysiology of septic shock

Signs and symptoms of childhood sepsis

• skin: mottled, non-blanching rash, cyanosis

• Breathing: low O2, high resp rate

• circulation: low systolic bp, high heart rate

• demeanour: not passing urine, sleepy, not feeding, vomiting repeatedly, altered behaviour

• Temp: high (might be normal)

• Bloods: high CRP, high WBC, high lactate

SEPSIS 6

1. Get senior physician

2. Give high flow O2

3. Get IV access and take blood culture

4. Give IV antibiotics

5. Give IV fluids

6. Monitor (NEWS score)

Sepsis give + take

Give:

• Oxygen

• Antibiotics

• Fluids

Take:

• Blood culture

• Urine output

• Serum lactate

Gram positive and negative microorganisms that can cause sepsis in neonates

+ve:

• Group B strep

• enterococci

• staph aureus

• listeria monocytogenes

-ve:

• haemophilus influenzae

• E.coli

Gram positive and negative microorganisms that can cause sepsis in infants + young children

+ve:

• Group A strep

• staph aureus

• strep pneumoniae

-ve:

• haemophilus influenzae

• neiserra meningitis

• bordetella pertussis

Gram positive and negative microorganisms that can cause sepsis in young children in hosptial

+ve:

• coagulase -ve staph

• MRSA

-ve:

• klebsiella spp

• pseudonomas aeurgiosa

• acienrobacer spp

How to prevent sepsis?

Primary:

• immunisation

• nutrition

• sanitisation

Secondary:

• early diagnosis

• early treatment

Tertiary:

• prevention of death