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pacemaker cells are located where?
SA node
What heart sound (S1) corresponds to the closing of the AV valves and marks the beginning of systole?
A) "Dub"
B) "Lub"
C) Opening of SL valves
D) End of diastole
B) "Lub"
The "Dub" sound (S2) is caused by the closure of which valves and marks the start of what phase?
A) AV valves; systole
B) SL valves; systole
C) SL valves; diastole
D) AV valves; diastole
C) SL valves; diastole
During the isovolumetric phase of the cardiac cycle:
A) Blood is rapidly filling the ventricles
B) Blood is being ejected into arteries
C) All valves are closed and no blood moves
D) Only the AV valves are open
C) All valves are closed and no blood moves
When the semilunar (SL) valves open, which phase is occurring?
A) Isovolumetric relaxation
B) Filling
C) Atrial contraction
D) Ejection
D) Ejection
During ventricular filling, which valves are open?
A) AV valves
B) SL valves
C) Both AV and SL valves
D) Neither valve type
A) AV valves
Which structure directly stimulates ventricular contraction?
A) AV node
B) Purkinje fibers
C) SA node
D) AV bundle
B) Purkinje fibers
During which part of the Wiggers diagram does ventricular pressure exceed aortic pressure, causing the aortic valve to open?
A) During ventricular filling
B) During isovolumetric contraction
C) At the end of ventricular systole
D) At the beginning of ejection
D) At the beginning of ejection
Blood is ejected from the heart during which phase of the cardiac cycle?
A) Atrial diastole
B) Isovolumetric contraction
C) Ventricular systole
D) Isovolumetric relaxation
C) Ventricular systole
Which valve prevents backflow from the right ventricle into the right atrium?
A) Pulmonary semilunar valve
B) Aortic semilunar valve
C) Tricuspid valve
D) Bicuspid valve
C) Tricuspid valve
Which chamber of the heart receives oxygenated blood from the lungs?
A) Right atrium
B) Left ventricle
C) Left atrium
D) Right ventricle
C) Left atrium
Which represents ventricular repolarization on an ECG?
A) P wave
B) QRS complex
C) T wave
D) U wave
C) T wave
Which of the following events does NOT occur when the semilunar valves open?
A) Ventricles are in diastole
B) Blood enters the pulmonary arteries and the aorta
C) AV valves are closed
D) Ventricular pressure exceeds arterial pressure
A) Ventricles are in diastole
Which of the following best describes isovolumetric contraction?
A) AV and semilunar valves are both open
B) Blood is rapidly ejected from the ventricles
C) All valves are closed; pressure increases
D) Atria are contracting
C) All valves are closed; pressure increases
Which wave on the ECG marks atrial depolarization?
A) Q wave
B) T wave
C) P wave
D) S wave
C) P wave
What causes the "dub" sound (S2) of the heart?
A) AV valves closing
B) Semilunar valves closing
C) Blood entering the ventricles
D) SA node firing
B) Semilunar valves closing
The pacemaker potential (spontaneous depolarization) of SA node cells is due to:
A) Fast Na⁺ influx
B) Slow Ca²⁺ efflux
C) Na⁺ influx through funny channels and Ca²⁺ influx
D) K⁺ influx
C) Na⁺ influx through funny channels and Ca²⁺ influx
Which pressure change causes the AV valves to close?
A) Atrial pressure drops below venous pressure
B) Ventricular pressure rises above atrial pressure
C) Aortic pressure drops below ventricular pressure
D) Pulmonary artery pressure drops below atrial pressure
B) Ventricular pressure rises above atrial pressure
The pulmonary veins carry:
A) Deoxygenated blood to the lungs
B) Deoxygenated blood to the heart
C) Oxygenated blood to the lungs
D) Oxygenated blood to the heart
D) Oxygenated blood to the heart
Which structure is considered the heart’s natural pacemaker?
A) AV node
B) AV bundle
C) SA node
D) Purkinje fibers
C) SA node
Which of the following would increase heart rate?
A) Parasympathetic stimulation
B) Vagus nerve activation
C) Acetylcholine release
D) Sympathetic stimulation
D) Sympathetic stimulation
What happens during ventricular systole?
A) Atria fill with blood
B) AV valves open
C) Semilunar valves open
D) Ventricles relax
C) Semilunar valves open
Which wave on an ECG represents atrial depolarization?
A) P wave
B) QRS complex
C) T wave
D) U wave
A) P wave
When are all heart valves closed?
A) During ventricular filling
B) During isovolumetric contraction and relaxation
C) During atrial systole
D) During ejection phase
B) During isovolumetric contraction and relaxation
What initiates the rapid depolarization phase in contractile cardiac muscle cells?
A) Na⁺ influx
B) Ca²⁺ influx
C) K⁺ efflux
D) Cl⁻ influx
A) Na⁺ influx
Which ion maintains the plateau phase in cardiac muscle action potentials?
A) Sodium
B) Potassium
C) Calcium
D) Chloride
C) Calcium
The amount of blood ejected from a ventricle in one beat is called:
A) Cardiac output
B) End-systolic volume
C) End-diastolic volume
D) Stroke volume
D) Stroke volume
The term “afterload” refers to:
A) The volume of blood in the ventricle at the end of diastole
B) The resistance the ventricle must overcome to eject blood
C) The heart rate x stroke volume
D) The passive filling of the ventricles
B) The resistance the ventricle must overcome to eject blood
Which of the following increases preload?
A) Increased venous return
B) Decreased ventricular filling
C) Dehydration
D) Hemorrhage
A) Increased venous return
What happens if the AV node is damaged?
A) Atrial contraction ceases
B) Ventricles beat faster than atria
C) SA node takes over
D) Ventricles contract at a slower, abnormal rate
D) Ventricles contract at a slower, abnormal rate
Which structure prevents backflow into the left ventricle?
A) Pulmonary valve
B) Tricuspid valve
C) Aortic semilunar valve
D) Mitral valve
C) Aortic semilunar valve
Which ion is primarily responsible for the depolarization phase in a neuronal action potential?
A) Ca²⁺ influx
B) K⁺ efflux
C) Na⁺ influx
D) Cl⁻ influx
C) Na⁺ influx
What ion is responsible for depolarization in pacemaker cells (SA node)?
A) Na⁺ via voltage-gated fast channels
B) Ca²⁺ via L-type calcium channels
C) K⁺ influx
D) Cl⁻ channels
B) Ca²⁺ via L-type calcium channels
The “funny” (If) channels in pacemaker cells allow:
A) K⁺ efflux
B) Na⁺ influx during repolarization
C) Na⁺ influx during spontaneous depolarization
D) Ca²⁺ influx during repolarization
C) Na⁺ influx during spontaneous depolarization
Which of the following best explains why cardiac muscle cannot be tetanized like skeletal muscle?
A) Rapid K⁺ efflux
B) Long absolute refractory period due to plateau
C) Short refractory period
D) Pacemaker cells reset quickly
B) Long absolute refractory period due to plateau
n contractile cardiac cells, what ion movement occurs during repolarization (phase 3)?
A) Na⁺ influx
B) Ca²⁺ influx
C) K⁺ efflux
D) Cl⁻ influx
C) K⁺ efflux
What ion movement brings neurons back to resting membrane potential after depolarization?
A) Na⁺ efflux
B) K⁺ efflux
C) Ca²⁺ influx
D) Cl⁻ efflux
B) K⁺ efflux
Which phase is absent in pacemaker action potentials compared to contractile cardiac cells?
A) Depolarization
B) Plateau phase
C) Repolarization
D) Resting membrane potential
B) Plateau phase
What is the resting membrane potential of most neurons?
A) +30 mV
B) 0 mV
C) –90 mV
D) –70 mV
D) –70 mV