PHARMACOLOGY - LECTURE

Earliest compilation of drugs, which was written by Emperor Shengnung in about 2,700 B.C.

Pen tsao

It describe penalties for malpractices of practitioner

Code of Hammurabi and Pen Tsao

Oldest record of egyptian drugs

Kahun papyrus

Compilation of disease conditions and prescriptions

Ebers papyrus

Assembled the library of clay tablets in Sumeria

Ashurbanipal

Father or Medicine

Hippocrates

Concept of the healing power of nature

Vis medicatrix nature

Formed the scientific basis of medicine

Aristotle

Systemically classifies medicinal plants

Theophrastus

Established the modern scientific method of naming plants or animals

Carolus Linnaeus

Compiled the 1st materia medica

Dioscorides

Deals with physiology and material medica

Galen

Compiled a treatise that included prescriptions for farm animals

Publius Vegetius

Classified drugs and poison

Geber Ibn Hjar

Compiled the 1st pharmacopeia

Valerius Cordus

Discovered the circulation of blood and indicated that drug were distributed to various parts of the body by this means

William Harvey

Make the 1st IV injection of drugs into a dog

Christopher Wren

Devised the 1st hypodermic needle and syringe

Alexander Wood

Introduced the clinical use of opium or laudanum

Theophrastus Bombastus Von Hohenheim

Isolated the narcotic substance of opium and called it morphine after the Roman God of Dream — Morpheus

Fredrich Serturner

Discovered the vaccine against small pox

Edward Jener

Established the foundation for modern pharmacology (drug-receptor relationship)

Francois Magendie

Showed the active ingredient of foxglove (for anasarcac edema)

Claude Bernard

Father of Pharmacology

Rudolph Buchheim

Established the 1st independent laboratory devoted exclusively to the study of pharmacology

Rudolf Buchheim

Father of Pharmacology in U.S.

John Abel

Father of chemotherapy

Paul Ehrlich

In 1910, reported the synthesis of arsphenamine which is an anti-syphilitic drug, for STD.

Paul Ehrlich

Observe the use of foxglove in the Tx of dropsy

William Withering

Isolated Penicillin

Alexander Fleming

Isolated Sulfonamides (antibacterial)

Gerhard Domagk

Isolated estrone/estrogen from female urine

Doisy and Butenandt

Isolated aldosterone from male urine

Butenandt

Discovered the steroid structure of progesterone

Slotta

Isolated thyroxine (T4)

Kendalll

Established the chemical structure of thyroxine (T4)

Harrington

Isolated and purify insulin

Banting and Best

Isolated adrenalin

John Abel

Antiseptic effect of chlorine in the effect of chlorine in the form of chlorinated lime

Ignaz Semmelweis

Use antiseptic in the field of surgery using carbolic lotion

Joseph Lister

Synthesized barbituric acid

Adolph Von Baeyer

Introduced the use of aspirin

Felix Holfman