A&P - Respiratory System

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231 Terms

1
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what are the major functions of the respiratory system
* O2 delivery and CO2 removal to/from blood
* acid base regulation (blood pH)
* immune protection
* smell/olfaction
* speech production
* thermoregulation
* warm and humidify inhaled air
* CV regulation
2
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what is respiration
process of supplying body with O2 and removing CO2 from the body
3
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what are the 3 processes of respiration
pulmonary ventilation

external respiration

internal respiration
4
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pulmonary ventilation
actual breathing

movement of air between atmosphere and alveoli
5
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inhalation/inspiration is ventilation of air from ------ to -------
atmosphere; alveoli
6
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exhalation/expiration is ventilation of air from ------- to -------
alveoli; atmosphere
7
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external respiration
gas exchange at the lungs (alveolar air sacs to pulmonary blood capillaries)
8
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in external respiration ____ is moving from alveolar air sacs to pulmonary blood capillaries
O2
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in external respiration ___ is moving from pulmonary blood capillaries to alveolar air sacs
CO2
10
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internal respiration
gas exchange at the tissue level (systemic blood capillaries and tissue cells)
11
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in internal inspiration ____ is moving from systemic blood capillaries to tissue cells
O2
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in internal inspiration ___ is moving from tissue cells to systemic capillaries
CO2
13
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what are the structural classifications of the respiratory system
upper or lower
14
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what are the functional classifications of the respiratory system
conducting zone or respiratory zone
15
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what structures/organs are part of the upper structural classification
* nose
* mouth
* pharynx
16
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what structures/organs are part of the lower structural classification
* larynx
* trachea
* primary bronchi
* secondary bronchi
* tertiary bronchi
* bronchioles
* terminal bronchioles
* respiratory bronchioles
* alveolar duct
* alveolar sac (alveoli)
17
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conducting zone refers to the function of
movement of air
18
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respiratory zone refers to the function of
work of gas exchange
19
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what structures/organs are part of the conducting zone (functional classification)
nose/mouth/pharynx all the way to terminal bronchioles
20
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what structures/organs are part of the respiratory zone (functional classification)
from respiratory bronchioles to alveolar sacs (alveoli)
21
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characteristics of the conducting zone
* thicker layers of epithelium tissue
* goblet cells producing mucus/cilia → mucociliary clearance
* thicker cartilage to keep airway patent
* less smooth muscle
22
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characteristics of respiratory zone
* thinner layers of epithelium tissue
* type I and type II alveolar cells
* immune protection from resident macrophages in alveoli
* little to no cartilage
* more smooth muscle
23
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where would nonkeratinized stratified squamous epi be in the system
* nose/mouth/pharynx
* larynx
24
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where would ciliated pseudostratified columnar epi be in the system
* nose
* pharynx
* larynx
* trachea
* primary, secondary, and tertiary bronchi
25
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where would ciliated simple columnar epi be in the system
bronchioles
26
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where would nonciliated simple columnar epi be in the system
terminal bronchioles
27
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where would simple cuboidal epi be in the system
respiratory bronchioles
28
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where would simple squamous epi be in the system
respiratory bronchioles and alveoli in alveolar sac
29
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what are the 4 cells of the respiratory zone
* type I alveolar cells
* respiratory membranes
* type II alveolar cells
* macrophages
30
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alveolar cells can also be known as
pneumocytes
31
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what do resident macrophages derive from
monocytes
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what function do resident macrophages derive from, where do they reside
immune protection, alveolar
33
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characteristics of type I alveolar cells
* simple squamous epi cells
* site of gas exchange
* more numerous alveoli cell
34
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characteristics of respiratory membrane
very thin fusion of alveolar (mainly type I) epithelium cells and pulmonary capillary endothelial cells
35
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characteristics of type II alveolar cells
* less numerous than type I
* produce a fluid called surfactant
* reduces surface tension of alveoli to help maintain patency
* maintain patency and openness
36
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what to membranes make of the serous membrane
parietal pleura and visceral pleura
37
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parietal pleura lines the
thoracic cavity
38
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visceral pleura lines the
direct surface of the lung
39
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what is between the two membranes in the serous membrane
serous fluid; helps reduce friction
40
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what is a spirogram measure with
spirometer
41
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what is 1
what is 1
inspiratory reserve volume/IRV (3000mL)
42
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what is 2
what is 2
tidal volume/Vt (500mL)
43
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what is 3
what is 3
expiratory reserve volume/ERV (1500mL)
44
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what is 4
what is 4
residual volume (1000mL)
45
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what is tidal volume
volume of air in lungs during restful breathing (500mL)
46
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what is expiratory reserve volume/ERV
maximum exhale after normal exhale (1500mL)
47
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what is inspiratory reserve volume/IRV
maximum inhale after normal inhale (3000mL)
48
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what is residual volume/RV
amount of air remaining after maximum exhale because we never get rid of all volume in lungs (1000mL)
49
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what are the 4 lung volumes
* IRV
* Tidal Volume (Vt)
* ERV
* Residual volume
50
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what are the 4 lung capacities
* Inspiratory capacity
* functional reserve capacity
* vital capacity
* total lung capacity
51
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what is a
what is a
inspiratory capacity/IC (3500mL)
52
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what is b
what is b
functional residual capacity/FRC (2500mL)
53
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what is c
what is c
vital capacity/VC (5000mL)
54
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what is d
what is d
total lung capacity/TLC (6000mL)
55
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what is inspiratory capacity/IC
max inhale after normal exhale (3500mL)
56
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equation for inspiratory capacity/IC
IC=Vt+IRV
57
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what is functional residual capacity/FRC
amount of air in lungs after normal exhale (2500mL), before the next inhale (slight pause)
58
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equation for functional residual capacity/FRC
FRC=ERV+RV
59
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what is vital capacity/VC
max inhale → max exhale (5000mL)
60
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equation for vital capacity/VC
VC=IRV+Vt+ERV
61
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what is total lung capacity/TLC
sum of all volumes
62
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equation for total lung capacity/TLC
TLC=IRV+Vt+ERV+RV
63
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what is minute ventilation
amount of air flow in 1 minute to the lungs
64
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equation for minute ventilation
minute ventilation Vb=Vt x fb (tidal volume\*respiratory rate)
65
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what is fb
breathing frequency/respiratory rate
66
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what is alveolar ventilation
amount of “fresh air” reaching alveoli in 1 minute
67
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what is dead space volume/Vd
amount of air in conducting zone

approximately equal to one’s ideal body weight (mL)
68
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equation for alveolar ventilation
Va= minute ventilation - (breathing frequency\*dead space volume)
69
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what is boyle’s law
pressure and volume are inversely related
70
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what is airflow equation
change in pressure (Patm-Palv) / resistance
71
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what is airflow at FRC
0
72
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what is Patm
atmospheric pressure

approx. 760 mmHg at sea level

0 mmHg at FRC
73
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what is Palv
alveolar pressure

approx. 760 mmHg at sea level

0 mmHg at FRC
74
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what is Pip
interpleural pressure

approx. 756 mmHg at sea level

\-4 mmHg at FRC
75
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what allows the pleura layers to move together when thoracic cavity increases or decreases
\-4 mmHg results in a vacuum suction
76
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what happens to the lungs if the size of the thoracic cavity increases
lungs expand
77
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what happens to the lungs if the size of the thoracic cavity decreases
lungs recoil/get smaller
78
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primary muscles involved in respiratory breathing
* diaphragm
* external intercostals
79
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accessory muscles for forced inhalation/inspiration
* sternocleidomastoid
* scalenes
80
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accessory muscles for forced exhalation/expiration
* internal intercostals
* external abdominal oblique
* internal abdominal oblique
* transverse abdominis
* rectus abdominis
81
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upon contraction the diaphragm moves ----- and ------ the size of the thoracic cavity
down; increases
82
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upon relaxation the diaphragm moves ------ and ------ the size of the thoracic cavity
up; decreases
83
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4 steps of restful inhalation/inspiration

1. neural input to skeletal muscles of inspiration
2. contraction of inspiratory muscles
3. lungs expand
4. air moves down its pressure gradient into lungs
84
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4 steps of restful exhalation/expiration

1. withdrawal of neural input to inspiratory muscles
2. relaxation of diaphragm and external intercostals
3. lungs recoil
4. air moves down pressure gradient
85
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what nerve innervates the diaphragm
phrenic nerve
86
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what nerve innervates the external intercostals
intercostal nerves
87
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upon contraction the external intercostals ------ ribs and ------ the size of the thoracic cavity
elevates; increases
88
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an increase in thoracic cavity size during inhalation causes the -------- ------- to --------
alveolar volume; increase
89
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if alveolar volume increases, alveolar pressure -------
decreases
90
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once lung expand in inhalation what is the pressure relation
Patm > Palv
91
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when Patm > Palv air moves where
into the lungs
92
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relaxation of diaphragm and external intercostals causes the size of the thoracic cavity to ------
decrease
93
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if thoracic cavity size decreases, then alveolar pressure -------
increases
94
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once lungs recoil in exhalation, what is the pressure relation
Palv > Patm
95
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when Palv > Patm air moves where
out of the lungs
96
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3 factors affecting ventilation
* alveolar surface tension
* lung compliance
* airway resistance
97
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if alveolar surface tension increases, work of breathing -----
increases
98
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what reduces alveolar surface tension
surfactant (type II cells)

* breaks up H20 from sticking
99
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what is lung compliance
stretchability of the lung
100
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increase in lung compliance means longs are more or less elastic/flexible
more flexible