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Block 2
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What is the purpose of a problem investigation?
to conduct a targeted assessment of a group of animals to investigate and address a specific problem
When are problem investigations initiated?
A increase in disease frequency
Production issues
Husbandry or population management issues
What are the steps for problem investigation?
Gather information
Verify a problem exists
Establish a case definition
Plan an investigation
Formulate hypotheses
Test the hypothesis
Design an intervention
What would be an immediate cause in a calf diarrhea outbreak?
Detection of an organism like Cryptosporidia
What would be an upstream cause of calf diarrhea?
Protocol drift- leads to an increase in production of calves with Failure of Passive Transfer of Immunity, if protocol drift is addressed it improves host resistance
How would you improve host resistance?
Colostrum protocols, nutrition, and treatment protocols
How would you decrease the infectious challenge?
Sanitation, bedding, amd housing management
What are the questions to ask for initial information gathering?
Who, What, When, Where
How many
Why is evidence gathered?
to verify a problem exists by comparing the “How Many” data against the farm’s accepted standards
How is evidence gathered?
by performing a physical exam
How is a case definition established?
based on the clinical signs and characteristics
How are herd level diagnostics decided?
sampling is planned based on the case definition and intended use of the results
What are on-farm associations?
evidence is gathered to demonstrate the link between a suspected upstream cause and the disease outcome
What is surveillance?
defined as the systematic collection, analysis, and interpretation of data
What is the objective of surveillance?
intervention in defined populations
What is monitoring?
essentially surveillance without an intervention threshold
What is screening?
involves testing apparently healthy individuals
What is critical goal of surveillance?
control and/or prevent diseases
What is early detection?
objective is to identify disease rapidly before significant spread to facilitate disease control
What are case findings?
identification of infected animals, flocks, or herds during a control program
What is measuring disease?
detect changes in the level of disease in the population
What is the objective of demonstrate freedom?
provide proof that a disease is not present in a population
this is crucial for international trade and for ending existing control measures
What are human health agencies that conduct surveillance?
State/regional public health
Centers for Disease Control and Prevention (CDC)
Food and Drug Administration (FDA)
What are animal health agencies that conduct surviellance?
State Department of Agriculture
USDA Animal and Plant Health Inspection Service (APHIS)
NAHLN
How is passive surveillance data collected?
utilizes samples collected primarily for another purpose
How is active surveillance collected?
utilizes samples collected specifically for use by surveillance program, involves an ongoing search for cases
How efficient and costly is passive surveillance?
high efficiency, simple and requires relatively few resources
How efficient and costly is active surveillance?
much more expensive to maintain, but may have high levels of completeness
How complete is passive surveillance?
possibility of incomplete data due to underreporting
Who uses passive surveillance?
majority of government systems
Who uses active surveillance?
needed for rare or hard-to-detect diseases
What is an example of passive surveillance?
Antibiograms
What is an example of active surveillance?
Monthly environmental sampling
What do antibiograms provide?
information about local antimicrobial resistance
What did the unexpected finding of west nile virus in the US lead to?
major mosquito control program implemented
How did testing for Bovine Tuberculosis shift in the US?
Slaughter Surveillance became the primary method for identifying infected herds
What did the surveillance system that eradicated brucellosis rely on?
Dairy Cattle Surveillance, which used the milk ring test to screen pooled milk samples 2-3 times per year
How do veterinary hospitals conduct surveillance for Hospital Acquired Infections (HAI)?
active environmental surveillance