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Metoprolol (β₁-selective)
MOA
MOA: ↓HR/contractility/AV conduction.
Metoprolol (β₁-selective)
Uses
Uses: HTN, angina, post-MI, HFrEF (succinate)
Metoprolol (β₁-selective)
AE
AE: Bradycardia, AV block, fatigue; masks hypoglycemia; hold HR <60 or SBP <90 (per facility).
Carvedilol (α₁ + β)
MOA
MOA: β₁/β₂ + α₁ block → ↓HR + vasodilation.
Carvedilol (α₁ + β)
Uses
Uses: HFrEF survival benefit, HTN
Carvedilol (α₁ + β)
AE
AE: Bradycardia, hypotension; caution in asthma/COPD.