Mosby Practice Exams

Benign Tumors Are:

• Encapsulated

• Rarely fatal

• Little effect on the host

• Differentiated

• Slow growth

• Low mitotic activity

• Little tissue destruction

• Abnormal proliferation of cells

Malignant Tumors Are:

• Unencapsulated

• Potentially fatal

• Substantial effect on the host

• Range from differentiated to undifferentiated

• Rapid growth

• High mitotic activity

• Potentially metastatic

• Invasive and destructive to tissue

• Abnormal proliferation of cells

What is curettage or exfoliation?

Scraping of cells for a biopsy.

What is an excisional biopsy?

Complete removal of suspicious tissue and margin.

What is an incisional biopsy?

Cutting into and taking a portion of suspicious tissue.

What is a fine needle aspiration (FSA)?

Use of a needle and syringe to draw out fluid from suspicious tissue.

What is a core biopsy?

Use of a large bore needle to withdraw a section of tissue.

What is an open biopsy?

A surgical procedure exposing the area of suspicious tissue for the visual investigation of a local area.

What is an Adenocarcinoma?

A malignant tumor of glandular epithelium.

What is a Myeloma?

Abnormal proliferation occurring in the bone marrow.

What is Leukemia?

Abnormal proliferation occurring in the bone marrow, especially the white blood cells.

What is an Osteosarcoma?

A malignant tumor occurring in bone.

What is a Rhabdomyosarcoma?

A malignant tumor occurring in striated muscle.

What is a Glioma?

A malignant tumor originating in the central nervous system.

Phase-specific cytotoxic chemotherapy drugs are:

• Effective on dividing cells

• One such class would be antimetabolites

• Examples include: 5-FU, Cytarabine, Floxuridine

• Causes myelosuppression

Phase nonspecific cytotoxic chemotherapy drugs are:

• Effective on nondividing cells

• One class would be alkylating agents

• Examples include: Nitrogen mustard, cisplatin, 6-mercaptopurine, cyclophosphamide

• Causes myelosuppression, kidney toxicity, nausea, and anorexia

What is Hyperplasia?

An increase in the number of cells and is associated with both malignant and benign tumors; typically a response to an acute injury.

What is Metaplasia?

The replacement of a cell type that usually is not present and is commonly associated with malignant conditions.

What is Anaplasia?

The loss of differentiation and is also associated with both malignant and benign conditions.

Mortality rates are based on the number of persons per ______ people in a population.

100,000

Any substance or agent