T helper cells chart
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12 Terms
What are the Th-polarizing cytokines for Th1?
IL-12, IFN-y
What are the Th-polarizing cytokines for Th2?
IL-4, IL-33, TSLP
What are the Th-polarizing cytokines for Th17?
IL6, IL-23, TGF-B
What are the Th-polarizing cytokines for Treg?
IL-2, TGF-B
What are Th1 defending against?
viruses, bacteria
What are Th2 defending against?
parasites
What are Th17 defending against?
bacteria, fungi
What are Treg defending against?
autoimmune
What are the adverse effects when Th1 is overactive?
granuloma, autoimmunity, hypersensitivity
What are the adverse effects when Th2 is overactive?
asthma, allergy, dermatitis, IgE-related diseases
What are the adverse effects when Th17 is overactive?
Rheumatoid, arthritis, inflammatory bowel disease
What are the adverse effects when Treg is overactive?
immune suppression (chronic viral infection; tumor)
Note 
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