inhibitors

inhibitors

molecules which can slow down or even stop metabolic reactions by interacting with the specific enzyme and deactivating the enzyme’s function

non-competitive inhibitors

bind to an allosteric site of an enzyme, thus changing the shape of the active site

increase in substrate concentration

substrate and inhibitor arent competing for the same site, increasing substrate concentration doesnt decrease the effect of the inhibitor

allosteric site

site away from the active site

are non- competitive inhibitors reversible

mostly irreversible, sometimes reversible depending on whether they bind briefly or permanently

competitive inhibitor

when a substance reduce the rate of activity of enzymes by competing with the substrate molecules for the enzymes active site

increase in inhibitor concentration

decrease in substrate concentration causes less competition for active site and inhibitors block the active site

is competitive inhibition reversible

reversible by increasing the concentration of substrate