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These flashcards cover key concepts related to the comparison of Action Potentials and Excitatory Postsynaptic Potentials (EPSPs), including their characteristics, effects, and the role of neurotransmitters.

What is the main difference in Amplitude between Action Potentials and EPSPs?

Action Potentials are all-or-none, whereas EPSPs are graded.

What occurs as a result of the binding of acetylcholine (ACh) in EPSPs?

The creation of an inward flow of Na+ that depolarizes the cell.

How do Action Potentials regenerate along the axon?

They are regenerated over the length of the axon due to positive feedback between depolarization and the opening of Na+ gates.

What is the effect of cholinesterase inhibitors on acetylcholine (ACh)?

They increase the amount of ACh in the synaptic cleft by blocking the action of acetylcholinesterase.

What is the maximum depolarization value for Action Potentials?

+40 mV.

Name one clinical use of cholinesterase inhibitors.

They are used to treat myasthenia gravis and Alzheimer's disease.

What happens during the refractory period of Action Potentials?

The neuron cannot fire another action potential immediately after the first.

What is the role of acetylcholinesterase (AChE)?

It inactivates ACh activity shortly after it binds to the receptor.

How do EPSPs differ in terms of conduction distance compared to Action Potentials?

EPSPs have a conduction distance of 1 to 2 mm, while Action Potentials are propagated along the entire axon.

What type of receptor opens ion channels indirectly using a G-protein?

Muscarinic ACh receptors.