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Flashcards for reviewing drug toxicities, electrolytes, and related concepts based on Mark Klimek's lecture.
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Lithium
Anti-mania drug used for bipolar disorder, specifically manic episodes. Therapeutic level: 0.6 to 1.2. Toxic level: >2.0
Lanoxin or Digoxin
Used to treat A-Fib and CHF. Therapeutic level: 1 to 2. Toxic level: >2
Aminophylline
Muscle spasm relaxer for the airway. Therapeutic level: 10 to 20. Toxic level: >20
Dilantin (phenytoin)
Seizure medication. Therapeutic level: 10-20. Toxic level: >20
Bilirubin
Breakdown product of Red Blood Cells. Normal level in adults: 0.2 to 1.2. Elevated level in newborns: 10 to 20. Toxicity in newborns: >20
Kernicterus
Excess bilirubin in the brain, occurring when the level in the blood gets >20. Can be deadly due to aseptic meningitis or encephalopathy.
Opisthotonos
Position a newborn assumes due to irritation of the meninges from kernicterus, presenting as a hyperextended posture. Is a medical emergency, place newborn on the side
Hiatal Hernia
A gastric emptying problem where gastric contents are regurgitated upward or backward into the esophagus, like a cow with two stomachs. Symptoms similar to GERD.
Dumping Syndrome
Gastric contents are dumped too quickly into the duodenum, right direction but at the wrong rate. Symptoms include Drunk, Shock, and Acute Abdominal Distress. Occurs 15-30 minutes after eating.
Kalemias
Kalemias do the same as the prefix (hypo-, hyper-), except for HR and urine output which go opposite.
Calcemia
Calcemias do the opposite as the prefix.
Magnesemias
Magnesemias do the opposite as the prefix.
Natremias
Hyponatremia = Volume overload. Hypernatremia = Dehydration
Hypernatremia
Hot, flushed, dry skin, thready pulse, rapid HR, associate with dehydration.
Hyponatremia
Crackles, distended neck veins, associate with fluid overload.
Paresthesia
Numbness and tingling.
Circumoral paresthesia
Numbness and tingling around the lips.
Paresis
Muscle weakness.
Treatment to High Potassium
Give D5W and regular insulin to decrease potassium, this will drive the potassium into the cell and out of the blood, temporary solution but quick
Kayexalate
Exchanges potassium for sodium, potassium is eliminated through feces and patient becomes hypernatremic, the downside is it takes hours to work; give D5W, Regular insulin, and Kayexalate at the same time