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Description
7 antigenic varieties of toxins (ABEF affect humans)
Pathogenesis
Blocks the release of acetylcholine resulting to flaccid paralysis
What is the result of blocking the release of acetylcholine
Flaccid paralysis
Pathogenesis - portal of entry
Food → bloodstream → P synapse of PNS
Pathogenesis - acetylcholine fusion
To be released of SNARE PROTEIN
Forms
Wound botulism
Forms
Food butilsm
Form
Infant botulism → honey
Treatment/ prevention
Respiratory support
Treatment
Trivalent antitoxin (types A,D,E)
Treatment
Botulinum immune globulin (big) → infants