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Kidney function
form urine
ureter function
transport urine
bladder function
store urine
urethra function
excrete urine
location of kidneys
R/L in the lumbar region behind the abdominal cavity - closer to posterior
enzyme the kidney produces and its function
renin (raises BP)
hormone kidney produces and its function
erythropoeitin - stimulates RBC production
suprarenal glands
glands on top of kidneys - regulates metabolism, blood pressure, stress response, and immune system response
prostate gland
only men have it - surrounds urethra
micturition
medical term for urinating (some is voluntary and some is involuntary)
ACE-inhibitors
angiotensin-converting enzyme inhibitors: block renin to lower BP
blood flow through kidney
abdominal aorta —> renal arteries —> kidneys —> renal veins —> IVC
renal cortex
outer cortex of kidneys
renal medulla
inner cortex of kidneys
renal pyramids
inside renal medulla
nephrons
working units in the kidneys
renal capsule
outer layer of the renal cortex
renal calyx
collecting “cups”, catch and collect urine from the renal pyramids
minor calyx
each pyramid has a major calyx and each major calyx has a minor calyx
renal pelvis
calyx dumps urine into the funnel shaped renal pelvis to ureter to bladder
function of nephrons
filter waste from blood, put filtered blood back into ciruclation by tubular reabsorption
parts of a nephron
Bowman'‘s capsule, proximal convoluted tubule, loop of henle, distal convoluted tubule, collecting tubule
renal artery
how blood enters kidney - branch of abdominal aorta
blood from renal artery goes where
into kidney —> Bowman’s capsule —> glomerulus
renal vein
how blood exits the kidney
glomerular filtrate
fluid from the nephron - mostly water, electrolytes, nutrients, and waste
main waste
urea
tubular reabsorption
everything that the nephron doesnt empty out
Antidiuretic hormone (ADH)
regulates the blood pH and promotes reabsorption of water
diuretics
help the body make more urine and eliminate excess fluid
kegel exercises
strengthen pelvic floor muscles to stop flow of urine
differences between male and female anatomy
female urethra - shorter and wider
male urethra - thinner and longer (carries urine and semen)
UTI risk - gender diff
females are much more likely to get UTIs because urethra is shorter and closer to vagina (females have separate reproductive and urinary tracts/men do not)
reno
kidney
nephro
kidney
glomerulo
glomerulus
pyelo
renal pelvisc
calio
calyx
uro
urine, urinary tract
urino
urine
uretero
ureterc
cysto
bladder
vesico
urinary bladder
urethro
urethra
UTI
urinary tract infection
UTI S/S
dysuria: pain or burning with urination
pyuria: pus-containing bacteria in urine
fever
cystitis
bladder infection
cystitis MOI
bacterial - E Coli
cystits S/S
pain in hypogastric region
fever
pyelonephritis
inflammation or infection of kidney
pyelonephritis MOI
urinary stasis - fecal matter in bladder to kidney - dehydration (not much urine, stays in kidney, bacteria grows)
pyelonephritis S/S
back pain, not emptying bladder regualrly or fully
urethritis
least serious, infection of urethra
urethritis MOI
STI usually
urethritis S/S
pain in urethra (females in vagina, males in penis), fever
difference between UTI and STI
STI - sexually transmitted, UTI - urinary tract
glomerulonephritis
inflammation of glomeruli and kidney; deep kidney infection; much less common; typically due to a bacterial infection somewhere else in the body
glomerulonephritis S/S
pain in lower back, fever, hypertension, edema, oliguria (leaky urine), hematuria (blood in urine), proteinuria (protein in urine),
Renal failure
kidneys fail - nephrons die
chronic renal failure (CRF)
end stage renal disease coexists; chronic kindey infection, autoimmune disease, kidney cancer
acute renal failure
happens quickly; injury shock, toxicity, infection
kidenys arent working so they cant eliminate potassium in blood
hyperkalemia
high potassium
acute tubular necrosis
nephrons become inflamed and die as they move into renal pelvis
acute tubular necrosis S/S
dehydration, edema, hypertension, anemia, uremia, electrolyte imbalance (increased K+)
Treatment for acute tubular necrosis
dialysis
hemodialysis
most common; arteries and veins are filtered by machnie
continuous ambulatory dialysis
type of dialysis that’s done at home during day
continuous cyclic dialysis
done at night while the patient sleeps
renal transplant
replacing diseased kidney with a healthy one from a donor
urinary stones
urinary lithiasis - mostly made of calcium
renal colic
medical term for pain from a kidney stone obstruction
hydronephrosis
obstruction blocking flow of urine causing the collection of urine to get backed up in renal pelvis
treatment of urinary stones
some pass on their own; hydrate; lithotripsy - vibration to mechanically break stones into smaller pieces
bladder cancer
most common - bladder carcinoma
bladder cancer S/S
painless hematuria
bladder cancer diagnosis
cytoscope, IV urography, pyelography
bladder cancer treatment
radiation, chemotherapy, immunosuppressant therapy, surgery, cystectomy, ostomy bag
urinalysis
clean catch urine is tested - color and turbidity, light yellow, turbid ( cloudy)
what would urinalysis look for
specific gravity (concentration or weight), pH, enzyme and hormone levels, blood, chemical components (glucose, ketones, hemoglobin)
cranial cavity endocrine glands
hypothalamus, pineal gland, pituitary gland
where in the brain is the hypothalamus
diencephalon
pituitary gland
anterior and posterior lobe, in the sell turcica (sphenoid bone), 6 hormones
pineal gland
releases melatonin; sleep cycle and circadian rhythm
endocrine glands in the neck
thyroid gland (T3 and T4) and parathyroid glands (parathyroid hormone)
what do the thyroid and parathyroid glands do
regulate calcitonin or calcium metabolism
endocrine gland in the thorax
thymus gland - top of ♡ by breastbone - secretes thymosin - immune
endocrine gland in the epigastric region
pancreas - releases glucagon and insulin - regulate glucose metabolism
lumbar endocrine glands
adrenal glands on top of kidney - secrete cortisol, aldosterone, norepinephrine, and epinephrine - fight or flight
reproductive endocrine glands
ovaries (estrogen and progesterone) and testes (testosterone)
2 categories of hormones
steroid hormones and amino acid hormones
steroid hormones
lipid based - sex glands and outer adrenal glands
amino acid hormones
protein based - other endocrine glands
how clinical conditions of the endocrine system arise (3 ways)
problems with hormone secretion, problem with target tissue, problem with endocrine glands themselves
six hormones of the anterior lobe of the pituitary gland
GH (growth hormone), TSH (thyroid stimulating hormone), ACTH (adrenocorticotropic hormone), LH (luteinizing hormone), PRL (prolactin)
2 hormones of the posterior lobe of the pituitary gland
antidiuretic hormone (ADH), and oxytocin
ADH (antidiuretic hormone)
helps with water conservation by kidneys to conserve water and vasoconstriction of blood vessels
oxytocin
female reproductive system; stimulates uterine contractions, initiates labor, promotes milk let down
T3 and T4
contain iodine bound to protein in the blood - iodine metabolism
parathryoid hormone
calcium metabolism - increasing blood calcium levels
outer cortex of adrenal gland hormones
cortisol, aldosterone, testosterone