redox and oxidation

Nicotinamide adenine dinucleotide in the oxidized form

NAD+ is

Nicotinamide adenine dinucleotide in the reduced form

NADH + H+ is

Niacin / Vitamin B3

In NAD+/H+ the active site is located on the Nicotinamide derived from

The A and B side

NADH has stereoisomers called

Gains an electron/H+

When something is reduced it

It loses a electron/H+

When something is oxidized

They are highly selective so stereochemistry is important

Different enzymes use different coenzymes of NAD+ or NADP+ and their different stereoisomers because

B1

Thiamine pyrophosphate

Aldehyde transfer

Beriberi

Thiamine is also known as … , coenzyme … , reaction type … , deficiency consequences …

B2

Flavin adenine dinucleotide (FAD)

Oxi-redox

Cheliosis and angular stomatitis

Riboflavin is also known as … , coenzyme … , reaction type … , deficiency consequences …

B6

Pyridoxal

Group transfer to/from amino acids

Depression, confusion, convulsions

Pyridoxine is also known as … , coenzyme … , reaction type … , deficiency consequences …

B3 / niacin

Nicotinamide adenine dinucleotide (NAD+)

Oxi-redox

Pellagra

Nicotinic acid is also known as … , coenzyme … , reaction type … , deficiency consequences …

B5

Coenzyme A

Acyl-group transfer

Hypertension

Pantothenic acid is also known as … , coenzyme … , reaction type … , deficiency consequences …

B7

Biotin-lysine adducts

ATP dependant carboxylation & carboxyl group transfer

Eyebrow rash, muscle pain, fatigue

Biotin is also known as … , coenzyme … , reaction type … , deficiency consequences …