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GH
Growth hormone
Where is GH released from?
The anterior pituitary gland
What cells does GH target?
Bone, muscle, and adipose tissue
What is the purpose of GH?
To promote growth, move amino acids through membranes, and increase cell size and rate of division
Which hormone stimulates the release of GH?
GHRH
What does GHRH stand for?
Growth hormone releasing hormone
Which hormone inhibits the release of GH?
SS
What does SS stand for?
Somatostatin
Where are GHRH and SS released from?
The hypothalamus
PRL
Prolactin
Where is PRL released from?
Anterior pituitary gland
What cells does PRL target?
Mammary glands
What is the purpose of PRL?
To stimulate milk production in women following childbirth and amplify the production of LH in men
Which hormone stimulates the production of PRL?
PRF
What does PRF stand for?
Prolactin releasing factor
Which hormone inhibits the release of PRL?
PIH
What does PIH stand for?
Prolactin inhibiting hormone
Where are PIH and PRF released from?
The hypothalamus
TSH
Thyroid stimulating hormone (thyrotropin)
Where does TSH go once it is released?
Through the bloodstream directly to the thyroid gland (located in the front of the neck, below the larynx)
Where is TSH released from?
The anterior pituitary gland
What does TSH do once it has reached the target cells (the thyroid gland)?
It binds to TSH receptor cells, signaling them to start producing thyroid hormones T3 and T4
T3
Triiodothyronine
T4
Thyroxine
What is the purpose of T3 and T4?
Boosts the energy released from carbs (by increasing basal metabolic rate), increases protein synthesis, and stimulates nerves
Which hormone stimulates the release of TSH?
TRH
What does TRH stand for?
Thyrotropin releasing hormone
ACTH
Adrenocorticotropic hormone (corticotropin)
Where is ACTH released from?
The anterior pituitary gland
Where does ACTH go once released?
Travels through the bloodstream directly into the adrenal cortex (located on top of the kidneys)
What does ACTH do once it reaches the adrenal cortex?
It binds to specific receptors to signal the production of cortisol ("stress hormone")
What does cortisol do?
Decreases rate of protein synthesis, increases the release of fatty acids, and stimulates glucose synthesis
Why/when is cortisol released?
Cortisol is released as part of your body's "fight or flight" stress response to increase glucose, energy, and blood pressure
Which hormone stimulates the release of ACTH?
CRH
What does CRH stand for?
Corticotropin releasing hormone
LH
Luteinizing hormone
Where is LH released from?
Anterior pituitary gland
Which hormone stimulates the release of FSH and LH?
GnRH
What does GnRH stand for?
Gonadotropin releasing hormone
Where is GnRH released from?
The hypothalamus
FSH
Follicle stimulating hormone
Where is FSH released from?
The anterior pituitary gland
Once released, where do FSH and LH go?
Through the bloodstream directly to the gonads
What does LH cause to happen?
Signals ovaries and testes to produce sex hormones (estrogen and testosterone) and triggers ovulation in women
What does FSH cause to happen?
In men, stimulates production of sperm; in women, causes development of follicles and secretion of estrogen
ADH
Antidiuretic hormone (vasopressin)
Where is ADH released from?
The posterior pituitary gland
Where does ADH go once released?
Targets the kidneys
What does ADH cause?
Reduces H2O excretion and, at high concentrations, causes vasoconstriction to help raise blood pressure
OT
Oxytocin
What does OT target once released?
Receptors in the uterine wall muscles and mammary glands
What does OT cause?
Causes contractions during childbirth and milk secretion after childbirth
Where is OT released from?
The posterior pituitary gland
CT
Calcitonin
Where is CT released from?
The thyroid gland
When/why is CT released?
When blood calcium levels are too high
What does calcitonin cause?
Lowers blood calcium levels by increasing excretion in kidneys and stimulates osteoblasts
PTH
Parathyroid hormone (parathormone)
Where is PTH released from?
The parathyroids
When/why is PTH released?
When blood calcium levels are too low
What does PTH cause?
Raises blood calcium levels by stimulating osteoclasts and signaling kidneys to conserve calcium
ALD
Aldosterone
Where is aldosterone released from?
The adrenal cortex
When/why is aldosterone released?
Influenced by low blood pressure, high potassium, or low sodium levels
What does ALD cause?
Causes kidneys to retain sodium and water while excreting potassium
Androgens
Group of male sex hormones
Where are androgens released from?
The adrenal cortex
GCG
Glucagon
Where is GCG released from?
Alpha cells in the pancreas
What does GCG cause?
Signals liver to break down glycogen to raise blood glucose, promotes fat breakdown
When is GCG released?
When blood glucose levels are low
Insulin
Insulin
Where is insulin released from?
Beta cells in the pancreas
What does insulin cause?
Lowers blood glucose by increasing synthesis of proteins and fats, moves glucose into cells
When is insulin released?
When blood glucose levels are too high
Somatostatin
SS
Which cells in the pancreas release SS?
Delta cells
What does SS do in the pancreas?
Helps regulate carbohydrates
EPI
Epinephrine (Adrenaline)
NE
Norepinephrine
Where are NE and EPI released from?
Adrenal medulla
What does EPI do?
Increases heart rate, vasodilation, cardiac output, airway dilation, activates brainstem reticular formation, raises blood sugar, increases metabolic rate
What does NE do?
Increases heart rate, vasoconstriction, increases systemic blood pressure, minor airway dilation, minor metabolic rate increase
Calcitriol
Calcitriol
Where is calcitriol synthesized/produced?
The skin
Where does calcitriol go once released?
Circulates to the intestines
What does calcitriol regulate?
Calcium and phosphate levels
MLT
Melatonin
Where is MLT released from?
The pineal gland
What is the purpose of melatonin?
Signals night time, regulates circadian rhythm
Thymosins
Ta1 and Tb4
Where are thymosins released from?
Thymus
What is the purpose of thymosins?
Promote development of lymphocytes, crucial for immune system development
E
Estrogens
Where are estrogens released from?
Ovaries
P4
Progesterone
Where is P4 released from?
Ovaries
What is the purpose of estrogen and progesterone?
Regulate menstrual cycle, support pregnancy, overall reproductive health
T
Testosterone
Where is T released from?
Testes