OCR A Synthetic Routes

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38 Terms

1
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primary alcohol to aldehyde

K2Cr2O7/H2SO4, distillation

2
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aldehyde to primary alcohol

NaBH4

3
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primary alcohol to carboxylic acid

K2Cr2O7/H2SO4, reflux

4
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aldehyde to carboxylic acid

K2Cr2O7/H2SO4, reflux

5
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alcohol to ester

carboxylic acid/conc. H2SO4 or acid anhydride

6
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carboxylic acid to ester

alcohol/conc. H2SO4

7
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ester to carboxylic acid

dilute acid, heat

8
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ester to carboxylate

OH-, heat

9
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carboxylic acid to acyl chloride

SOCl2

10
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acyl chloride to carboxylic acid

H2O

11
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acyl chloride to ester

alcohol

12
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acyl chloride to primary amide

NH3

13
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acyl chloride to secondary amide

primary amine

14
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aldehyde to hydroxynitrile

NaCN(aq)/H+(aq)

15
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hydroxynitrile to carboxylic acid

H2O/HCl, heat

16
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nitrile to carboxylic acid

H2O/HCl, heat

17
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ketone to hydroxynitrile

NaCN(aq)/H+(aq)

18
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hydroxynitrile to amine

H2/Ni

19
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Nitrile to amine

H2/Ni

20
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secondary alcohol to ketone

K2Cr2O7/H2SO4, reflux

21
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ketone to secondary alcohol

NaBH4

22
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alcohol to haloalkane

sodium halide/H2SO4

23
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haloalkane to alcohol

NaOH(aq)

24
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alkane to haloalkane

halogen, UV

25
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alkene to alkane

H2/Ni

26
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alkene to haloalkane

hydrogen halide

27
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alkene to alcohol

H2O (steam)/H3PO4

28
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alcohol to alkene

H3PO4 or H2SO4, heat

29
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haloalkane to nitrile

CN-/ethanol

30
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haloalkane to amine

NH3/ethanol

31
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benzene to methylbenzene

CH3Cl/AlCl3

32
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benzene to nitrobenzene

conc. HNO3, conc. H2SO4

33
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nitrobenzene to phenylamine

Sn/conc. HCl

34
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phenylamine to 2,4,6-tribromo phenylamine

Br2

35
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benzene to bromobenzene

Br2/AlBr3 or Fe or FeBr3

36
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benzene to cholorobenzene

Cl2/AlCl3 or Fe or FeCl3

37
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Benzene to phenylethanone

CH3COCl/AlCl3

38
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phenylethanone to phenylethanol

NaBH4