S: a large gland made up of parenchyma composed of hepatocytes, lobule structure, central vein
F: the hepatocytes that make up the liver have dual secretory and metabolic functions, exocrine secretions (secretory product = bile), endocrine secretions (secreted into blood: albumin, lipoproteins, non-immune alpha and beta globulins, prothrombin, glycoproteins, glucose, triiodothyronine)
L: beneath diaphragm, on top of stomach, right kidney and intestines