cell to cell junctions

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adheren junctions

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  • cadherin- Ca2+ dependent adhering molecules

  • forms a homophilic interaction which mskes strong links between cells

  • links actin cytoskeleton

  • cadherin→ catenin→ actin→ myosin

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desmosomes

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  • cell- cell junctions

  • cadherins and intermediate filaments

  • plentiful in heart muscle and epidermis

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6 Terms

1
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adheren junctions

  • cadherin- Ca2+ dependent adhering molecules

  • forms a homophilic interaction which mskes strong links between cells

  • links actin cytoskeleton

  • cadherin→ catenin→ actin→ myosin

2
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desmosomes

  • cell- cell junctions

  • cadherins and intermediate filaments

  • plentiful in heart muscle and epidermis

3
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hemidesmosomes

  • attach cells to basal lamina

  • integrins and intermedate filaments

4
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focal adhesions

e complex protein structures that connect the cell's internal cytoskeleton to the extracellular matrix (ECM). They play a crucial role in cell adhesion, migration, and signaling.  

5
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pemphigus

  • desmoglein is a caherin which holds together kerarinocytes in epidermis

  • pemphigus is autoimmune skin blistering

6
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role of tight junctions

  • to prevent fluid and membrane flow

  • variable extent

  • transcellular transport

  • paracellular transport

<ul><li><p>to prevent fluid and membrane flow</p></li><li><p>variable extent</p></li><li><p>transcellular transport</p></li><li><p>paracellular transport</p></li></ul><p></p>