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lectures 1-3 plus mystery of sleep vid
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Is Hibernation sleep
no because its seasonal not circadian
Most of what we know about sleep comes from studying
mammals
do animals all have the same sleep cycles?
no there are lots of differences between species in REM sleep
Phylogentic Order
refers to the arrangement of organisms based on their evolutionary relationships, often depicted through phylogenetic trees that illustrate common ancestry
NOT associated with sleep parameters
Altrical vs Precocious
altrical species (animals that need help after being born, need their parents) need more REM rather than precocious species
What is the primary function of non-REM sleep in relation to energy use?
Non-REM sleep is associated with reduced energy expenditure and a lower metabolic rate.
How does non-REM sleep affect metabolic rate?
It lowers metabolic rate, contributing to overall energy conservation during sleep.
Is REM proportional to brain size?
no
Do mammals have REM and non-REM?
all mammals experience both REM and non-REM
-maybe not cetaceans (Dolphins or whales)
-relative proportion of REM and non-REM differs across species
-general characteristics very similar across species
-egg-laying originally thought to not have REM, but they do
Only non-mammals to have REM and non-REM
Birds
REM and slow wave sleep homeostatically regulated as in mammals
-Song birds have more REM, increased REM following new song
No evidence of REM
Reptiles, Amphibians and Fish
EEG differ from mammals ands birds
-sleep behavuiour has large spikes in EEG
-spikes increase after sleep deprivation
-lack slow waves
-no evidence of REM
Topor
a passive state in which insects enter
Does sleep change over lifespan?
yes, drastically
Sleep in Utero
-entirely in REM, brains develop
-more than half of first year of life is sleep
non rem is stable until about age of
10
REM is reduced at age ____ (again)
60
3 Types of sleep
Quiet sleep (QS, like slow wave sleep (SWS))
Active sleep (AS, like REM)
intermediate sleep (IS)
____ and ____ alternate in a 90 min cycle (50-60 for newborns)
QS and AS (quiet and REM sleep)
2 types of wake
quiet-wake, resting and really drowsy
Active wake
Babies sleep ____ and their sleep wave cycle is
16-18 hours
sleep wave cycle is 3-4hrs, goes with feeding times
For Babies, active sleep becomes REM
after about 12 weeks
By age __ sleep is similar to adults but a little bit longer
10
Adolescent sleep
-teens need closer to 9-11 hours
-most only get 6-7
=chronic sleep debt
-things are made worse by going to bed late and waking late
Adult Sleep
-cycle 90-110 min
Light sleep on average 55%
-SWS on average 20%
-REM on average 25%
Senior Sleep
-sleep becomes fragmented
-50% of seniors, naps reappear
-longer sleep onset latencies (longer time falling asleep)
-nocturnal awakenings are more frequent and longer
-mild reduced total sleep time across 24 hr cycle
-shorter first non-rem Rem cycle
-sleep efficiency goes from 96% downwards (quality gets worse)
Delta activity occurs
in stage 3 sleep
As you age time spent in stage __ increases, why?
stage 1
less REM, more lighter stages of sleep
Stage 2 in adulthood
goes down in earlier adulthood, than increases again into older years
Time spent in stage 3 sleep
age 35, sws goes down in males, but higher in females as they age
Sleep efficiency reduces..
to 96% as children and then to 80% as senior
Waves when awake are called
alpha waves
Waves in each sleep stage
theta waves
sleep spindles and k-complex
(slow wave sleep) delta waves
Sleep spindles
little burst of movement 12-16hz
k-complex
still dont know 100% what they do..
but theyre a negative reflection after a positive. Wave spikes up then drops down
Histograph
shows sleep stages
Most of deep sleep occurs
Most of REM occurs
Most of deep sleep occurs during first half of night.
Most of deep sleep occurs in second half of the night. After first two sleep cycles, REM periods get longer.
Sleep is measured through, what system helps measures where to place the electrodes
electroncephalography (EEG) -on a cap thing
10/20 system, tells you measurements from center of the head
polysomnography (PSG) - what does that look like/contain?
what is usually done at a sleep test
sensor on nose to measure air flow
sensors on face/scalp measures eye movements and brain activity
elastic belt sensors on chest and belly measures amount of effort to breath
sensor on finger -blood oxygen
wires transmit data to computer
Characteristics of LS (long sleepers)
introverted + depressed
some neurotic traits, some self-confidence problems, anxiety, more bodily aches
-prolonged sleep duration may be associated with an increased risk of dementia
Characteristics of SS (short sleepers)
Extraverted, energetic/aggressive
-more conforming, denial of problems, abitious, decisive and out-going
3 aspects of sleepiness
Introspective
physiological
manifest
Introspective aspect of sleepiness and how it is measured
is the self assessment of your internal state. -how sleepy are you?
measured with scales such as:
-Epworth sleepiness scale (trait) stable and enduring
-stanford sleepiness scale (state) and temp and contex dependent
-various analog scales
Physiological aspect of sleepiness and how it is measured
is your body’s biological need to sleep (like hunger and thirst) using things like eeg
measured by the multiple sleep latency test (MSLT)
Manifest aspect of sleepiness and how it is measured
is the behavioural component as shown in performance deficits, errors, inattention, and even being overcome by sleep.
measured by maintenance of wakefulness test (MWT) -psychomotor vigilance task
Factors influencing sleep positions
body temp
ambiant temp
body type (size)
physiological conditions
laterality (left or right handed)
Daily activity level
surface of your bed
Kleitman
1952 decided to start charting eye movement in sleep at uni of Chicago, passed along his work later
REM= dream periods
Describe the average Sleep cycle
Muscles start to relax, brainwaves become slower
after ~ 80 min REM occurs and we dream for ~10 min
Another cycle follows, this time with ~20min REM
In next 90 min cycles we descend only to stage 2 (lighter sleep) but REM periods lengthen each time.
in 7-8 hours should have ~4-5 REM cycles
During REM
Rapid eye movement
Dream state
Active paralyses of all our muscles (this is not relaxation)(except to breath) and for men, penile erection during REM.
brain is more active during REM than when awake.
Nightmares
Normal paralyses of REM gives way to the intensity of the nightmare
Various kinds of sleep disorders known as
Parasomnias
-abnormal behaviour between wakefulness and non-REM
Suprachiasmatic Nucleus
-20,000 neurons form a biological clock that influences wakefullness
rhythm of rising and setting sun
circadian rhythm