Cancer_ CRISPR
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8 Terms
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What does cas9-RNA complex do first?
recognize and bind to a 3-nucleotide sequence called PAM.
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What does PAM stand for?
proto-spacer adjacent motif
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LOF =
nonsense, framshift, deletion
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GOF=
missense
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why insert gene for NY-ESO-1 receptor?
The NY-ESO receptor can grab cancer cells
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results of the cancer CRISPR study?
10% efficiency
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What is epigenetics?
the study of changes in genetic code from enviornment
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What is required when editing DNA with CRISPR?
The DNA sequence of the genomic locus to be edited
Note 
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