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Biomolecules
Large molecules essential for life, including carbohydrates, lipids, proteins, and nucleic acids.
Water
Polar molecule essential for life, with unique properties like cohesion, adhesion, and high specific heat.
Carbohydrates
Organic compounds composed of carbon, hydrogen, and oxygen; primary source of energy.
Lipids
Hydrophobic molecules used for energy storage, membrane structure, and signaling.
Proteins
Polymers of amino acids; responsible for structure, function, and regulation of tissues and organs.
Amino Acids
Building blocks of proteins; consist of a central carbon, an amino group, a carboxyl group, and a variable R group.
Enzymes
Proteins that catalyze biochemical reactions by lowering activation energy.
Nucleic Acids
DNA and RNA; store and transmit genetic information.
DNA
Deoxyribonucleic acid; molecule that carries genetic information.
RNA
Ribonucleic acid; involved in protein synthesis and gene regulation.
Nucleotide
Building blocks of nucleic acids; composed of a sugar, phosphate group, and nitrogenous base.
Hydrogen Bonding
Weak bonds between hydrogen and electronegative atoms; important in DNA structure and water properties.
pH
Measure of the concentration of hydrogen ions in a solution; affects enzyme activity and chemical reactions.
Dehydration Synthesis
Chemical reaction in which two molecules are joined by removing a water molecule.
Hydrolysis
Reaction in which water is added to break down a molecule into smaller units.
Prokaryotic Cells
Cells without a nucleus or membrane-bound organelles.
Eukaryotic Cells
Cells with a nucleus and membrane-bound organelles.
Plasma Membrane
Phospholipid bilayer that separates the cell’s interior from the outside environment.
Cytoplasm
Gel-like substance inside the cell where organelles are located; site of metabolic reactions.
Nucleus
Membrane-bound organelle containing the cell’s DNA and controlling gene expression.
Mitochondria
Organelles responsible for energy production through cellular respiration.
Chloroplasts
Organelles in plant cells that conduct photosynthesis.
Endoplasmic Reticulum (ER)
Network of membranes involved in protein and lipid synthesis.
Golgi Apparatus
Organelles that modify, sort, and package proteins and lipids for transport or secretion.
Lysosomes
Membrane-bound organelles containing enzymes that break down waste materials and cellular debris.
Ribosomes
Structures responsible for protein synthesis, found in the cytoplasm or attached to the rough ER.
Cytoskeleton
Network of protein fibers that provides structural support, shape, and movement to cells.
Cell Wall
Rigid outer layer of plant, fungal, and bacterial cells, providing structure and protection.
Vesicles
Membrane-bound sacs used to transport materials within or outside the cell.
Endocytosis
Process by which cells engulf extracellular material by wrapping the plasma membrane around it.
Exocytosis
Process by which cells expel materials through vesicles fusing with the plasma membrane.
ATP (Adenosine Triphosphate)
Main energy currency of the cell, used in various biochemical processes.
Cellular Respiration
Process by which cells break down glucose to produce ATP.
Glycolysis
First stage of cellular respiration; breakdown of glucose into pyruvate, producing a small amount of ATP.
Citric Acid Cycle (Krebs Cycle)
Second stage of cellular respiration; occurs in mitochondria and produces high-energy electron carriers.
Electron Transport Chain
Final stage of cellular respiration; generates ATP through oxidative phosphorylation.
Fermentation
Anaerobic process that allows cells to generate ATP when oxygen is unavailable.
Photosynthesis
Process by which plants, algae, and some bacteria convert light energy into chemical energy.
Chlorophyll
Green pigment in chloroplasts that absorbs light energy for photosynthesis.
Light-dependent Reactions
Stage of photosynthesis where sunlight is used to produce ATP and NADPH.
Calvin Cycle
Light-independent reactions of photosynthesis; converts carbon dioxide into glucose using ATP and NADPH.
Enzyme-Substrate Complex
Temporary molecule formed when an enzyme binds to its substrate.
Activation Energy
The energy required to start a chemical reaction.
Feedback Inhibition
Regulatory mechanism in which the end product of a pathway inhibits an enzyme involved earlier in the pathway.
Signal Transduction Pathways
Processes by which a cell responds to external signals through a series of molecular events.
Receptors
Proteins that receive and bind to signaling molecules, initiating cellular responses.
G-Protein Coupled Receptors (GPCRs)
Membrane receptors that activate G proteins in response to signaling molecules.
Tyrosine Kinase Receptors
Membrane receptors that phosphorylate tyrosine residues to trigger signaling pathways.
Cyclic AMP (cAMP)
Second messenger molecule involved in the activation of signal transduction pathways.
Apoptosis
Programmed cell death; essential for development and maintaining cellular health.
Mitosis
Process of cell division that results in two genetically identical daughter cells.
Meiosis
Type of cell division that produces gametes (sperm and egg), reducing the chromosome number by half.
Cell Cycle
Series of stages (G1, S, G2, and M) that a cell goes through to divide.
Interphase
Stage of the cell cycle where the cell grows, replicates DNA, and prepares for division.
Prophase
First stage of mitosis where chromatin condenses into chromosomes.
Metaphase
Stage of mitosis where chromosomes align in the center of the cell.
Anaphase
Stage of mitosis where sister chromatids are pulled apart toward opposite poles.
Telophase
Final stage of mitosis where the nuclear envelope reforms around the separated chromatids.
Cytokinesis
Division of the cytoplasm and organelles between daughter cells at the end of mitosis.
Checkpoints
Regulatory points in the cell cycle that ensure proper cell division and DNA integrity.
Cyclins and Cyclin-dependent Kinases (CDKs)
Proteins that regulate the progression of the cell cycle.
Gene
Unit of heredity, a sequence of DNA that codes for a protein or RNA.
Alleles
Different forms of a gene that may produce variations in traits.
Homozygous
Having two identical alleles for a particular gene.
Heterozygous
Having two different alleles for a particular gene.
Genotype
Genetic makeup of an organism; combination of alleles for a given trait.
Phenotype
Observable traits of an organism resulting from its genotype.
Punnett Square
Tool used to predict the genotypes and phenotypes of offspring from two parents.
Mendel’s Laws of Inheritance
Principles of heredity based on Gregor Mendel's experiments with pea plants: Law of Segregation and Law of Independent Assortment.
Law of Segregation
Mendel's law stating that each allele for a gene separates into different gametes.
Law of Independent Assortment
Mendel's law stating that genes for different traits are inherited independently of each other.
Codominance
A type of inheritance in which both alleles for a gene are fully expressed.
Incomplete Dominance
A type of inheritance where the heterozygous phenotype is an intermediate blend of the two homozygous phenotypes.
Polygenic Inheritance
Inheritance pattern where multiple genes contribute to a single trait.
Sex-linked Traits
Traits controlled by genes located on sex chromosomes, often exhibiting different inheritance patterns in males and females.
X-inactivation
Process by which one X chromosome in female mammals is randomly inactivated.
DNA Replication
Process of copying DNA before cell division; ensures each daughter cell has identical genetic material.
DNA Polymerase
Enzyme that synthesizes new DNA strands during replication.
Helicase
Enzyme that unwinds the DNA double helix ahead of the replication fork.
Ligase
Enzyme that joins Okazaki fragments on the lagging strand during DNA replication.
Okazaki Fragments
Short segments of DNA synthesized on the lagging strand during replication.
Transcription
Process by which an RNA molecule is synthesized from a DNA template.
RNA Polymerase
Enzyme that synthesizes RNA during transcription.
mRNA (messenger RNA)
RNA molecule that carries genetic information from the DNA to the ribosome for protein synthesis.
Codon
A sequence of three nucleotides in mRNA that codes for a specific amino acid.
tRNA (transfer RNA)
RNA that brings amino acids to the ribosome during translation.
Ribosome
Organelles that facilitate protein synthesis by reading mRNA and linking amino acids.
Translation
Process by which mRNA is translated into a sequence of amino acids to form a protein.
Mutations
Changes in the DNA sequence that can lead to genetic variation or disorders.
Point Mutation
Mutation involving a single nucleotide; can lead to a change in the amino acid sequence.
Frameshift Mutation
Mutation that shifts the reading frame of the mRNA, usually causing significant changes in the protein.
Operon
Cluster of genes in prokaryotes regulated by a single promoter; includes an operator, promoter, and structural genes.
Lac Operon
An operon involved in the metabolism of lactose in bacteria; regulated by lactose availability.
Epigenetics
Study of changes in gene expression caused by mechanisms other than changes in the DNA sequence.
Histone Modification
Chemical modifications to histone proteins that affect DNA packaging and gene expression.
RNA Splicing
Process of removing introns from pre-mRNA and joining exons together to form mature mRNA.
Introns
Non-coding regions of mRNA that are removed during RNA splicing.
Exons
Coding regions of mRNA that remain after splicing and are translated into protein.
Natural Selection
Process by which individuals with advantageous traits survive and reproduce more effectively than those without.
Fitness
Measure of an organism's ability to survive, reproduce, and pass on its genes.