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30 Terms

1
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5 chemicals required for life

  1. Water

  2. Carbon (food)

  3. Nitrogen (DNA, RNA, amino acids/proteins)

  4. Phosphorous (ATP)

  5. Sulphur

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Which nitrogenous bases are purines/pyrimidines and how many hydrogen bonds between them all?

Purines (double ring structure): Adenine and Guanine

Pyrimidines (single ring structure): Cytosine and Thymine/Uracil

3 hydrogen bonds: Guanine and Cytosine 

2 hydrogen bonds: Adenine and Thymine/Uracil

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What direction is DNA replicated/RNA synthesised?

5’ to 3’ with new nucleotides being added at the 3’ end

4
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Examples of monosaccharides, disaccharides and polysaccharides

Monosaccharides

  • glucose

  • fructose

  • galactose

  • ribose

Disaccharides

  • maltose

  • sucrose

  • lactose

Polysaccharides

  • starch

  • cellulose

  • glycogen

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Name the bonds between monomers of macromolecules 

Nucleotides: Phosphodiester bond 

Polysaccharides: Glycosidic bond 

Triglyceride (3 fatty acid chains bound to glycerol): Ester bond 

Polypeptides: Peptide bond

6
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Compare and contrast the isomers of glucose

  1. Alpha glucose: hydroxyl group below

  • Makes up glycogen, starch

  1. Beta glucose: hydroxyl group above 

  • Makes up cellulose

<ol><li><p>Alpha glucose: hydroxyl group below</p></li></ol><ul><li><p>Makes up glycogen, starch</p></li></ul><ol><li><p>Beta glucose: hydroxyl group above&nbsp;</p></li></ol><ul><li><p>Makes up cellulose</p></li></ul><p></p>
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Compare and contrast the different types of starch

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Describe cellulose

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Compare different types of fatty acids

  • Saturated fatty acids (no double bonds)

  • Unsaturated fatty acids (double bonds in hydrocarbon chains)

    • Mono (one double bond) vs poly (multiple double bonds)

    • Cis (hydrogen on the same side) vs trans (hydrogens have opposing orientation)

<ul><li><p>Saturated fatty acids (no double bonds)</p></li><li><p>Unsaturated fatty acids (double bonds in hydrocarbon chains)</p><ul><li><p>Mono (one double bond) vs poly (multiple double bonds)</p></li><li><p>Cis (hydrogen on the same side) vs trans (hydrogens have opposing orientation)</p></li></ul></li></ul><p></p>
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Draw and label a diagram of a peptide bond between two amino acids 

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List the bonds in each structure of proteins

  1. Primary: peptide bonds (polypeptides)

  2. Secondary: hydrogen bonds (alpha helix vs beta pleated sheet)

  3. Tertiary: disulfide bridges (covalent), hydrogen bonds, ionic bonds, and hydrophobic interactions (between R groups to achieve 3D structure)

  4. Quaternary: Bonds between multiple polypetide chains

    1. Conjugated: combine with non amino acid material

    2. Non conjugated: only made up of amino acids

<ol><li><p>Primary: peptide bonds (polypeptides)</p></li><li><p>Secondary: hydrogen bonds (alpha helix vs beta pleated sheet)</p></li><li><p>Tertiary: disulfide bridges (covalent), hydrogen bonds, ionic bonds, and hydrophobic interactions (between R groups to achieve 3D structure)</p></li><li><p>Quaternary: Bonds between multiple polypetide chains </p><ol><li><p>Conjugated: combine with non amino acid material</p></li><li><p>Non conjugated: only made up of amino acids </p></li></ol></li></ol><p></p>
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What happens to proteins in different pH and temperatures?

Low pH: Denaturation 

High pH: Denaturation 

Low temp: Inactive 

High temp: Denaturation

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Identify organelles found in prokaryotes vs eukaryotes

All living things have:

  • Plasma membrane

  • Cytoplasm

    • Cytosol

  • DNA

  • Ribosomes

<p><strong>All living things have: </strong></p><ul><li><p>Plasma membrane</p></li><li><p>Cytoplasm</p><ul><li><p>Cytosol</p></li></ul></li><li><p>DNA</p></li><li><p>Ribosomes</p></li></ul><p></p>
14
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List different types of membrane proteins

Integral proteins: Embedded in lipid bilayer, ampiphatic, mostly transmembrane but some are only on one side

  • Channel proteins: Form channels/pores for membranes to pass through

  • Carrier proteins: Undergo conformational change to transport molecules 

  • Aquaporins: hydrophilic inside channel to allow for transport of water molecules without need for osmosis 

Peripheral proteins: Hydrophilic, membrane surface

  • Receptors: receive chemical signals and act as binding sites (for hormones or neurotransmitters)

15
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Define ventilation terms

  • Total lung capacity: Total volume of air in the lungs after taking the biggest breath

  • Forced vital capacity: After taking the biggest inhale, how much of that air you can exhale

  • Residual volume: The amount of air your lungs must have in them to avoid collapse

  • Tidal volume: Volume of air that moves in and out of lungs in a normal breath

  • Inspiratory reserve: Difference between tidal volume and total lung capacity

  • Expiratory reserve: Difference between tidal volume and residual volume

<ul><li><p>Total lung capacity: Total volume of air in the lungs after taking the biggest breath</p></li><li><p>Forced vital capacity: After taking the biggest inhale, how much of that air you can exhale</p></li><li><p>Residual volume: The amount of air your lungs must have in them to avoid collapse </p></li><li><p>Tidal volume: Volume of air that moves in and out of lungs in a normal breath</p></li><li><p>Inspiratory reserve: Difference between tidal volume and total lung capacity</p></li><li><p>Expiratory reserve: Difference between tidal volume and residual volume</p></li></ul><p></p>
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Compare arteries, veins and capillaries

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Describe the two different types of speciation

  1. Allopatric: speciation in different environments (geographical isolation)

  2. Sympatric: speciation within the same environment (temporal isolation or behavioural isolation)

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Describe adaptive radiation

Adaptive radiation: Common ancestor splitting into multiple species due to different variations exploiting different ecological niches.

  • Minimises competition

  • ex: Darwin’s finches developing different shaped beaks in line with the food source on their island

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Describe polyploidy 

Polyploidy: When homologous chromosome sets contain more than two (are not diploid)

<p>Polyploidy: When homologous chromosome sets contain more than two (are not diploid)</p>
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Define anthropogenic

Anthropogenic: Caused by humans

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Describe formula for Simpson’s Diversity Index

High index when there is a high

  • Richness (lots of different species)

  • Evenness (not dominated by one species)

<p>High index when there is a high</p><ul><li><p>Richness (lots of different species) </p></li><li><p>Evenness (not dominated by one species) </p></li></ul><p></p>
22
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Direction of DNA processes

  • DNA sense/coding strand 5’ to 3’

  • DNA antisense/template strand 3’ to 5’

    • DNA read in 3’ to 5’ direction for transcription (antiparallel to the mRNA being synthesised in a 5’ to 3’ direction)

23
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Lytic vs lysogenic cycle of the bacteriophage lambda

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Neonicotinoid effect on neural signalling

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Sister chromatids vs homologous chromosomes

Sister chromatid: identical copies of a single chromosome

  • created during DNA replication, and are joined at the centromere

Homologous chromosomes: pair of chromosomes

  • one inherited from each parent

  • same size, shape, and genes

  • but may carry different versions (alleles) of those genes

<p><u>Sister chromatid</u>: <span><span>identical copies of a single chromosome</span></span></p><ul><li><p><span><span>created during DNA replication, and are joined at the centromere</span></span></p></li></ul><p></p><p><u>Homologous chromosomes:</u> <span><span>pair of chromosomes</span></span></p><ul><li><p><span><span>one inherited from each parent</span></span></p></li><li><p><span><span>same size, shape, and genes</span></span></p></li><li><p><span><span>but may carry different versions (alleles) of those genes</span></span></p></li></ul><p></p>
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Describe mature mRNA

Mature mRNA is a product of post transcription modification in the nucleus

  • 5’ cap and poly A tail added

  • exons spliced together

The poly A tail slows the rate of degradation

<p>Mature mRNA is a product of post transcription modification in the nucleus </p><p></p><ul><li><p>5’ cap and poly A tail added </p></li><li><p>exons spliced together</p></li></ul><p></p><p>The poly A tail slows the rate of degradation </p><p></p><p></p>
27
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Describe epigenetic tags

Epigenetic tags: Chemical modifications that cause some genes to be activated and others to be silenced.

  • Doesn’t affect the gene itself, just the pattern of gene expression

  • Facilitates differentiation as all cells have the same genome but their function is dependent on their expression

  • Can be passed to offspring

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Describe methylation 

Methylation: A type of epigenetic tag that involves the addition of a methyl group

  • Methylation of the promoter region of a gene inhibits transcription 

  • Methylation of histone proteins can change how available DNA is to transcription factors 

29
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Xylem and phloem in plant root vs plant stem

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Describe disruptive, stabilising and directional selection

Disruptive: Both extreme phenotypes are favored over the intermediate one

Stabilising: The intermediate phenotype is favored, and extreme variations are selected against.

Directional: One extreme phenotype is favored, causing the population's average trait value to shift over time.

<p><strong>Disruptive: </strong><span><span>Both extreme phenotypes are favored over the intermediate one</span></span></p><p></p><p><strong>Stabilising: </strong><span><span>The intermediate phenotype is favored, and extreme variations are selected against.</span></span></p><p></p><p><span><strong><span>Directional:</span></strong><span> One extreme phenotype is favored, causing the population's average trait value to shift over time.</span></span></p>

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