Neural Stem Cells - NOT ON EXAM

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cool information to know

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stem cells

  • nervous system has limited ability to repair itself

  • neurons are post-mitotic

  • stem cell features

    • self-renewing

    • unspecialized (undifferentiated cells) - can mature into type neuron or glia

    • populate developing and degenerating areas of the CNS

<ul><li><p>nervous system has limited ability to repair itself </p></li><li><p>neurons are post-mitotic</p></li><li><p>stem cell features </p><ul><li><p>self-renewing </p></li><li><p>unspecialized (undifferentiated cells) - can mature into type neuron or glia </p></li><li><p>populate developing and degenerating areas of the CNS </p></li></ul></li></ul><p></p>
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stem cell sources

  • embryonic tissue

  • adult from endogenous sources:

    • bone marrow stem cells

    • adult neural cells

<ul><li><p>embryonic tissue </p></li><li><p>adult from endogenous sources: </p><ul><li><p>bone marrow stem cells </p></li><li><p>adult neural cells </p></li></ul></li></ul><p></p>
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adult neural cells

  • olfactory bulb, hippocampus, ventricles, cervical spinal cord

  • have been shown to be responsive to injury and will migrate to damaged area

  • limited resource and difficult to obtain

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stem cells and cell replacement therapy

  • implications as treatments for many diseases

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stem cell sources: skin

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