19/08 Lecture 16 - Genetic Changes

Synonymous SNP

This variant causes no change in the amino acid expressed

Missense SNP

This variant causes a change in the amino acid expressed

Nonsense SNP

This variant inserts a stop codon at an inappropriate locus

Inframe mutation

This describes the gain or loss of single amino acids

Frameshift mutation

This shift causes all codons after to be uneven and read incorrectly

Codon redundancy

This describes the existence of multiple codons coding for the same amino acid

Regulatory variant

This type of variant alters the promotor region of a gene

Intron variant

This type of variant alters the intron region of a gene

Intergenic variant

This type of variant alters the DNA sequence between genes