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community pharmacy equipment
bar code scanner, robotic vial filler, automated pill counter
institutional pharmacy equipment
laminar flow hood, tallest, kitcheck
capsule
meds in which active ingredient is enveloped in a hard or soft gelatin shell
lozenges (troches)
hard, sugary, candy-like dosage form
ointment
small amount of water in a large, oily base
creams
small amount of oil in a water base
lotion
small amount of oil in a water base; thinner than creams
suppositories
med contained in an inactive base that will melt once inserted into the body
elixir
dissolved med in water and ethanol
syrups
sugar-based solution
extract
powder derived from an animal or plant after solvent is evaporated
tincture
alcoholic or hydroalcoholic liquid that contains plant extract
spirit
alcoholic or hydro alcoholic liquid w volatile, aromatic ingredients
suspension
drug does not dissolve in the base, leaving small solid particles floating; may need to be reconstituted or mixed w water before dispensing; shake before dispensing
enema
used to deliver med rectally to bypass GI tract
intrathecal
med to be injected around or in the spinal cord
warfarin drug interactions
NSAIDs, antibiotics, fish oil, coenzyme 10, garlic supplements, ginko blob, vitamin K
warfarin side effects
excessive bruising/bleeding
NSAIDs drug interactions
lithium or methotrexate —> causes toxicity
warfarin —> risk of bleeding
HMG-CoA reductase inhibitors interactions
grapefruit inhibits metabolism leading to muscle damage
benzodiazepines + hydrocodone drug interaction
respiratory depression
clopidrogel + PPIs drug interaction
reduce effectiveness of clopidrogel
antibiotics drug interaction
anticoagulants —> inc risk of bleeding; reduce effectiveness of birth control
SSRIs or SNRIs + MAOIs interaction
cause serotonin syndrome
digoxin + diuretics interaction
inc risk of digoxin toxicity
lithium drug interactions
alcohol, NSAIDs, methotrexate
therapeutic index
comparison of the amt of a drug that causes the desired effect vs the amt that causes toxicity
narrow therapeutic index
when the window between positive effect and toxic effect is small
ISMP high alert meds
Institute for Safe Medication Practices; list o high alert meds based on practice setting
drug allergy
immune system mistakenly identifies a med as a harmful invader and overreacts to it
side effects
predictable reaction to a medication; related to how the med works
prescription reqs
patient name, patient phone num, patient DOB, administration route, physicians office name, address, phone num, physicians signature, sig (directions for use), date written, med name, strength, quantity, dose, and dosage form, refill info
origin codes
how the prescription was produced and delivered
origin code —> 1
written; typed and printed or handwritten
origin code —> 2
phone; a prescriber phones in a prescription to a pharmacist
origin code —> 3
electronic; prescriber sends an electronic transmission of prescription thru software package
origin code —> 4
faxed; pharmacy must retain transmission info for records
DAW code —> 0
generic substitution permitted; pharmacy can dispense generic in place of brand meds when available
DAW code —> 1
brand name medically necessary; prescriber mandates pharmacy dispenses brand name med
DAW code —> 2
patient requests brand name
controlled substances act (CSA) of 1970
establishes the DEA and forms drug schedules
drug schedule
based on accepted medical use in treatment in US and likelihood of causing dependence
addiction
disorder characterized by compulsive drug use; repeated use alters brain functions
drug abuse
habitual taking of addictive substances
tolerance
when a patient’s run to a drug is progressively reduced, require an increased dose to achieve the desired effect
withdrawal
onset of symptoms resulting from discontinued use of a substance
psychological dependence
dependency of the mind to continue the same pattern of behavior
physical dependence
awareness of withdrawal symptoms such as seizures, sweating, and tremors when use of a substance is discontinued
C-I medications
no accepted medical use
C-II medications
high dependence factor; no refills; no transferring from one pharmacy to another; expire 6 months after they are written
C-III medications
moderate dependence factor; can be prescribed 5 refills; can be transferred from pharmacy to pharmacy ONCE; expire 6 months after they are written
C-IV medications
less dependence factor; can be prescribed 5 refills; can be transferred from pharmacy to pharmacy ONCE; expire 6 months after they are written
C-V medications
slight dependence factor; can be prescribed 5 refills; can be transferred from pharmacy to pharmacy ONCE; expire 6 months after they are written
NCLM (non-controlled legend medications)
all other prescription medications
OTC
non-prescription med; may be prescribed up to a year’s worth of refills; can be transferred pharmacy to pharmacy for an unlimited amount of times; expire one year after the date they are written
sig
shorthand notation of directions written by providers
adjudication
submission and subsequent response of a claim to an insurance company
manufacturer’s label
includes med’s brand name, generic name, strength, quantity, manufacturer, lot number, expiration date, NDC code
prescription label
includes med name, strength, quantity, directions, patient’s name, prescriber’s name, prescription #, expiration date, refills remaining, pharmacy name, pharmacy phone #
accuracy scanners
commonly used to verify that the correct med is used to fill prescriptions
automatic med counters
used to streamline the dispensing process by eliminating the need to count meds by hand
counting trays
used to count prescriptions for dispensing
safety caps
all prescriptions should be dispensed with child-proof safety caps by default except nitroglycerin and non-oral dosage forms
auxiliary labels
provide info to patient about how to take meds
look-alike sound-alike meds
meds with similar looks or sounds; use tall-man lettering to avoid confusion
counseling
involves pharmacist talking to patients to ensure they feel comfortable taking their meds
reference manuals
used to fill a prescription for a patient or med you aren’t used to
medicare
funded by tax dollars; provides healthcare services for elderly (65+), disabled individuals, or those with end stage renal disease
medicare part A (“hospital insurance”)
covers inpatient (pt is formally admitted to stay in the hospital) and hospital costs
medicare part B (“medical insurance”)
covers outpatient services (pt does not need to stay in hospital to receive care)
medicare part C (“medicare advantage plan”)
alt way to receive benefits
medicare part D (“prescription insurance”)
covers prescription meds
doughnut hole
when spending exceeds a certain amount, medicare requires that patients pay a higher % for meds
catastrophic coverage
medicare drops the % paid for meds after reaching a certain amount
medicaid
funded by federal and state dollars; insurance for low-income, pregnant, elderly, and disabled individuals and children
tricare
funded by federal dollars; provides healthcare service to active and retired armed forces and fam members
non-profits
federal funding provided to non-profit hospitals and research institutes
formulary
list of drugs that are preferred for any given plan; designed by physicians, pharmacists, and administrators
open formulary
allows patients any covered med within formulary; largest # of covered meds
preferred formulary
entices patients to use preferred meds by offering lower prices in a three-tier system
three-tier system
provides generic med at a low cost, preferred brand meds at slightly higher cost, and non-preferred meds at substantially higher cost
closed formulary
does not cover any drug not listed on the formulary; commonly seen w restrictive HMOs like Medicaid
quantity limit
place strict guidelines on how many dosage units can be dispensed in a specific day supply
step therapy
when the formulary only allows for the med prescribed to be covered if the patient has alr taken other (less expensive) meds first
prior authorization
provider answers qs abt a patient’s condition and based on the info provided, a med may or may not be covered
copay
the amount due from the customer for a claim
benefit
the amount paid by the insurance for a claim
deductible
the amount the customer must pay, per plan year, to receive any benefit from insurance
premium
the amount the customer must pay monthly to have insurance
average wholesale price (AWP)
the average price paid by pharmacy to buy a drug from the wholesaler; typically much higher than the actual cost paid
maximum allowable cost (MAC)
the max the PBM will pay for a generic med
drug utilization review (DUR)
software checks for drug interactions, age alerts for pediatric meds, over/underutilization of meds, therapeutic duplication
specific gravity
ratio of a liquid’s density at a certain temp compared to the density of water at that temp; no units
ratio strength
compares 2 ingredients in a mixture
percentage strength
compares 2 ingredients in a mixture
daily dose
total dose a patient will take in a day; dose x frequency
day supply
how long a prescription should last a patient; insurance companies use it to determine how often to pay for meds; total quantity / daily dose
quantity sufficient
total quantity for prescription; day supply x daily dose
Clark’s Rule
child’s dose (mg) = [weight of child (lbs) x adult dose (mg)] / 150 (lbs)
Young’s Rule
child’s dose (mg) = [child’s age (yrs) x adult does (mg)] / [child’s age + 12 (yrs)]