Bchm Exam 4: Pentose Phosphate Pathway

pentose phosphate pathway purpose

alternative pathway for glucose oxidation

where does the pentose phosphate pathway occur

cytosol of the cell

products of the pentose phosphate pathway

pentoses for nucleotide synthesis and NADPH for biosynthesis of fatty acids

what is the starting molecule for the pentose phosphate pathway

glucose-6-phosphate

what are the functions of NADPH

cholesterol synthesis, fatty acid synthesis, and reduction of glutathione

what is the first step of the pentose phosphate pathway

glucose-6-phosphate to 6-phosphogluconate

what is lost/created during the first step of the pentose phosphate pathway

NADP+ is reduced to NADPH

what is the enzyme of the first step of the pentose phosphate pathway

glucose-6-phosphate dehydrogenase

what is important to remember about the first step of the pentose phosphate pathway

it is the rate-limiting step

what is the second step of the pentose phosphate pathway

6-phosphogluconate to ribulose-5-phosphate

what is created/lost during the second step of the pentose phosphate pathway

NADP+ is reduced to NADPH

what is the enzyme of the second step of the pentose phosphate pathway

6-phospogluconate dehydrogenase

the first two steps of the pentose phosphate pathway are considered

oxidative and irreversible

what is the last step of the pentose phosphate pathway

ribulose-5-phosphate to ribose-5-phosphate

what is important to remember about the product of the pentose phosphate pathway

ribose-5-phosphate is used in nucleotide synthesis, rapidly dividing cells, reversible reaction