ILE Depression according to Dr. Jackson

If a patient is on an MAOI what ADR should you monitor for

anticholinergic effect

What is the gold standard for depression rating scale

HAM-D

Etiology of depression

Genetics

What is the best way to assess AD efficacy

Rating scale

What percentage decrease is defined as a response

50%

What precentage of patient prematurely d/c AD

50%

Which AD is dangerous to overdose

TCA

Which meds cause depression

Isotretinoin, benzodiazepine, beta blocker, oral contraceptiv

It takes 5 months to see which of the following with the use of antidepressant?

Recovery

NDRI off label

weight gain, sedation, sexual dysfunction

3 most common ADR of SNRI

Headache, nausea, anxiety

common ADR in TCA and NDRI

Seizure

which class has DDI with Tramadol

MAOI

A patient comes into your Emergency Room after eating a reuben and french fries at a local restaurant. The patient complains of a fever, headache, stiffness, and sweating. He is taking a beta blocker, a statin and an MAOI. What do you suspect?

HTN crisis

What should be monitored for NaSSA

Elevated TG

Which should be monitored for efficacy

Adherence, ADR, Risk of danger to onself and others, use of marijuan

Which PHQ-9 is associated w a mild depression

5-9

best treatment for mild depression

psychotherapy

Treatment should last at least one year in patients who have how many episodes of depression?

1 or 2

TCA and SNRI can cause this when overdosed

CNS depression

Which class causes HTN

SNRI, NDRI

Which drug blocks NE and DA

Bupropion (Wellbutrin)

which class improves nerve pain

TCA, SNRI

Which class improves sleep

TCA, NaSSA, SARI

Which class causes weight loss

NDRI

Which class causes sexual dysfunction

SSRI, SNRI, NaSSA, Serotonin modulator, TCA, MAOI

An increase in norepinephrine in the synaptic cleft leads to which of the following adverse effects?

HTN

Which class is associated with seizure

NDRI, TCA

Which class has histaminic activity

TCA, NaSSA, SARI

Which class caues hepatotoxicity

SARIW

hich clas causes HTN

SNRI

which class initially worsens anxiety

SSRI, SNRI

How long does it take for antidepressants to treat depressive symptoms?

4-6 weeks

What is the goal of treating depression?

Remission

Which class x cause sexual dysfunction

NDRI, SARI, NaSSA

What is the ADR of NaSSA

Weight gain, sedation

Does SSRI cause insomnia

Yes

What antidepressant class causes the greatest risk of anticholinergic activity?

TCA