histo 4- pancreas

the endocrine pancreas is made up of

islets of langerhan

what stain is used to distinguish the cell types in the islets of langerhan

mallory-azan staining

what color are a cells w/ mallory-azan staining

red

what color are B cells w/ mallory-azan staining

brown/orange

what color are D cells w/ mallory-azan staining

blue

where are A cells located in the islet

periphery

a cells secrete

glucagon

what stain is used for A cells

grimelius silver stain

where are B cells located in the islet

center

B cells secrete

insulin

where are D cells located in the islet

periphery

D cells secrete

somatostatin

types of pale cells in the islet of langerhan

F cell

D-1

EC cell

F cell secretes

pancreatic polypeptide

D-1 cells secrete

VIP

EC cells secrete

substance P

secretin

motilin

PSNS stimulation of the islets

inc glucagon and insulin

SNS stimulation of the islets

glucagon secretion

inhibits insulin

describe the circulation of the islets

periphery perfused first (A and D cells)

then center (B cells)

the inhibitory effect of insulin on glucagon secretion is carried out by the insulin where

in general circulation