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neuron
interconnected information processors made of many parts that work together
Functions/types of neurons
receive sensory info (afferent)
process info and integrate with prior experience (interneurons)
output to guide our actions (efferent)
soma
the cell body of the neuron responsible for maintaining the life of the cell, contains nucleus and branches out into dendrites
dendrites
a neuron's branching extensions that receive messages and conduct impulses toward the cell body and down the axon
axon
the extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons or to muscles or glands
action potential
electrical signal that travels down the axon
terminal buttons/branches
contain synaptic vesicles that contain neurotransmitters, form junctions with other cells
mylein sheath
a segmental layer of fatty tissue that covers many axons and helps speed neural impulses
synapse
areas where two neurons meet (gap between them)
glial (glia) cells
support neurons (stimulate growth, repair damage, keep them in place)
step by step action potential
dendrites- receive info from other neurons send to soma
if cell depolarizes enough and reaches threshold an action potential fires
impulse moves done axon, vesicles pushed to terminals and releases ntm to synapse
refractory period of rest
refractory period
when the cell is going back to rest (polarized), cannot fire another action potential
all-or-none principle
the law that the neuron either fires an action potential or doesn't
polarized
highly negative charge in the soma (when resting)
depolarized
positive ions go inside when soma gets info,
Neurotransmitters
Chemicals released into synapse that transmit information from one neuron to another, have to fit into a certain receptor (dopamine ntm can only fit into a dopamine receptor
excitatory EPSP
post synaptic neuron fires an action potential (depolarized)
inhibitory IPSP
post synaptic neuron doesn't fire an action potential (polarized)
Reuptake
ntm are recycled by resting neuron (reeled back in)
agonist
mimics an ntm (binds to receptor to activate), prevents reuptake, increases production and release
antagonist
blocks receptor sites, prevents ntm from bonding, decreases production and release
acetylcholine
A neurotransmitter that enables learning and memory and voluntary muscle contraction, used by PNS
acetylcholine deficiency
alzheimer's disease
dopamine
experience of pleasure (reward pathway), initiation of voluntary muscle movement
dopamine deficiency and excess
d: parkinsons
e: schizophrenia, addiction
norepinephrine
arousal, alertness, attention, used by SNS, associated with mood
norepinephrine deficiency
d: depression, anxiety
serotonin
mood, sleep, appetite,
serotonin deficiency and excess and fluctuation
d:depression
e:mania
f:BPD
GABA
inhibitory (don't fire) reduce CNS, involved in sleep and arousal
GABA deficiency
d: huntington's disease
Glutamate
excitatory (keep firing), strengthens neural connections, learning, doing things faster with less focus,
endorphins
reduce pain, euphoria,
peripheral nervous system
sensory and motor neurons that connect CNS to rest of your body; relay between brain, spine and rest of body
autonomic nervous system
controls involuntary functions that happen automatically in the body
sympathetic nervous system
part of the autonomic nervous system that arouses the body, mobilizing its energy in stressful situations, fight or flight, increases heart and breathing rate
parasympathetic nervous system
part of the autonomic nervous system that calms the body, conserving its energy, rest and digest, decreases heart and breathing rate,
somatic nervous system
controls voluntary movements of skeletal muscles, and communication to sense organs
afferent neurons (sensory neurons)
neurons that TAKE IN information from the senses to the CNS, feelings and senses (skin and eyes)
efferent neurons (motor neurons)
neurons that take information from the brain to the rest of the body CARRY OUT INFO from CNS to PNS, guide our actions
central nervous system
contains spine and brain, controls most functions of the body and mind, processes, interprets and stores info, issues orders to muscles, glands, and organs
brain
The mass of nerve tissue that is the main control center of the nervous system
spinal cord
Nerves that run up and down the length of the back and transmit most messages between the body and brain VIA INTERNEURONS
reflex/reflex arc
reflex: quick involuntary responses, only conrolled by spine
RA: afferent neurons bring in sensory input to spine, spine makes efferent neurons have reaction, then info goes to the brain and pain is felt
EEG
monitoring electrical activity of the brain (brain waves) by attaching electrodes on the scalp, non invasive procedures, done for sleep studies
CT/CAT
Imaging technique where a computer coordinates and integrates multiple X-rays of a given area, x-ray of brain structure CANNOT SEE TISSUE (horizontal slice, many angles put together) ex: see tumors and broken bones, appendectomy
PET
Involves injecting individuals with radioactive glucose and monitoring chemical activity in different areas of brain (will ask to do tasks to see which areas are activated/blood goes to) ex: criminals may be mad at seeing bunnies when normal people would be happy
MRI
Magnetic fields and radio waves map out brain structure SHOWS TISSUE ex: ligaments in knee
fMRI
Monitors blood flow and oxygen in the brain to identify areas of high activity when patients are engaged in a certain behavior or task
Lesioning
Destroying a small part of brain tissue, electrodes used to burn tissue and disable structure NOT USED ON HUMANS (unless to sever corpus callosum for seizures) mostly rats for research very invasive procedure
ESB
Deep brain stimulation activates a brain structure with weak electric currents sent to an implanted electrode very invasive ex: increase dopamine to help Parkinsons
TMS
Temporary enhancement or depression of activity in a specific area of the brain using a magnetic coil on a small paddle non-invasive
Hindbrain
Primitive Brain: Medulla, Pons, Cerebellum, Reticular Formation
Medulla
vital functions (HR BP breathing)
Pons
sleep and dreams (REM sleep), should be stimulated at night
cerebellum
balance and coordination
Reticular formation
network of cells control alertness, attention, and arousal
locus coeruleus
nucleus within RF, stress and panic responses
Substantia Nigra and striatum
initiation of movement has lots of dopamine receptors
Forebrain
Thalamus, hypothalamus, limbic system
LImbic system
emotion center: contains hippocampus and amygdala
thalamus
"Central relay station" for all senses except smell, afferent neurons go here and then to another lobe to process information
hypothalamus
Biological drives ex: hunger, thirst, body temperature, sleep
hippocampus
Formation of new memories, creates memories, does not store them, not responsible for recall
amygdala
Emotional reactions especially fear and aggression
AP ONLY basal ganglia
Important to smooth muscle movement and actions works with cerebellum involved in procedural memories for skills
Cerebrum/Cerebral Cortex
Controls Complex Thought processes, connects left and right hemispheres
Cerebral Hemispheres
Right hemisphere controls left side of body left hemisphere controls right side of body CONTRALATERAL
corpus callosum
bundle of fibers that connect left and right hemispheres, allows halves to communicate
association cortices
allows to communicate, responsible for thought, memory, and learning in combination with forebrain, integration of sensory info puts everything together to make it make sense
occipital lobe
contains visual cortex, seeing
parietal lobe- contains sensory cortex
contains somatosensory cortex (touch pressure pain)
temporal lobe
contains auditory cortex
frontal lobe
motor cortex- movement
prefrontal cortex- higher order thinking (decision making, planning)
mirror neurons
Neurons that fire when we watch others perform actions, brain firing is almost as if we are doing it
neurogenesis
the formation of new neurons
Plasticity
ability of brain to strengthen existing neural connections and form new connections, ability to rewire brain ex: when someone goes blind their hearing is heightened, when brain gets split L and R hemispheres work independently
Right/Left Brain
Cerebral lateralization
L Hemisphere
controls right side, speech and language, logic, analysis, math skills
Brocas Area
located in left frontal lobe, physical production of speech and language
Aphasia and types
aphasia- language deficit due to stroke/brain injury
brocas-Broken speech
wernickes-What are you saying?
Wernicke's area
located in left temporal lobe, comprehension and interpretation of speech and language
R Hemisphere
Controls movement of L side of body; nonverbal, creative/artistic, spatial patterns and facial recognition, emotion- both expressing and reading others
Split Brain Reasearch
split brain=severed/lesioned corpus callosum, R+L hemi can no longer communicate
AP ONLY: study by sperry and gazzaniga
endocrine system
glands that secrete hormones (chemicals) into the bloodstream, and are absorbed by organs and glands throughout the body
hormones
the chemicals released by endocrine glands into the bloodstream
pitutary gland
master gland of endocrine system (in brain)
oxytocin
hormone that regulates reproductive behaviors (trust, bonding, cooperation, empathy, "love" hormone, reduce stress, melt when you get hugged)
chromosomes
strands of DNA that carry genetic info (46 tot)
zygote
fertilized egg (first 2 weeks)- DNA is assembled
genes
DNA segments that carry genetic info
Homozygous vs. Heterozygous
2 of the same genes vs 2 different genes
dominant vs recessive
dominant: only needs one allele to show, overrides the recessive gene, expressed in heterozygous condition
recessive: needs 2 of the same alleles, masked in heterozygous condition, only displayed in homozygous condition
genotype vs phenotype
genotype- genetic makeup
phenotype- what we see, ways in which genotypes are manifested in observable characteristics
polygenic inheritance
characteristics that are influenced by more than one pair of genes (ex. skin color, widows peak is monogenic)
identical (monozygotic) twins
1 fertilized egg that splits (exact same genotype)
fraternal (dizygotic) twins
develop from separate fertilized eggs. They are genetically no closer than ordinary brothers and sisters
genetic mapping
The process of determining the location and chemical sequence of specific genes on specific chromosomes.
epigenetics
study of how genetics are controlled by factors other than DNA, how does nurture affect nature
Darwin
survival of the fittest