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Integumentary system
The organ system that includes skin, hair, nails, and associated glands and receptors.
Stratified epidermis
A multi-layered structure of the skin that provides protection from abrasions and environmental damage.
Keratin
A protein produced by keratinocytes that waterproofs the skin and protects against heat, microbes, and chemicals.
Melanin
A pigment produced by melanocytes that contributes to skin color and protects against UV radiation.
WBC in dermis
White blood cells located in the dermis that contribute to the immune response.
Sebaceous gland
Gland in the skin that secretes sebum, which moistens and waterproofs the skin.
Eccrine sweat glands
Sweat glands located all over the body, primarily involved in regulating body temperature.
Apocrine sweat glands
Sweat glands concentrated in specific areas, such as the axilla, and become active at puberty.
Hypodermis
Also known as the subcutaneous layer, it anchors the skin to underlying structures and contains adipose tissue.
Nail matrix
The tissue under the base of the nail that is responsible for nail growth.
Jaundice
A yellowish skin color caused by the buildup of bilirubin in the blood.
Cyanosis
Bluish coloration of the skin and nails due to inadequate oxygen circulation.
Erythema
Redness of the skin resulting from dilated blood capillaries during inflammation or injury.
Stratum corneum
The outermost layer of the epidermis, composed of dead, keratinized cells.
Langerhans cells
Immune cells in the epidermis that act as macrophages to engulf pathogens.
Merkel cells
Specialized cells in the epidermis that function as touch receptors.
Hair follicle
A small tubular cavity in the skin where hair develops.
Arrector pili
Small smooth muscles that attach to hair follicles and cause hairs to stand up, creating 'goosebumps'.
Skin wound healing
The process through which the skin repairs itself after injury, involving different phases such as inflammatory and proliferative phases.
Basal cell carcinoma
A common type of skin cancer that rarely metastasizes, arising from basal cells in the epidermis.
Malignant melanoma
A life-threatening form of skin cancer that arises from melanocytes and can metastasize rapidly.
Keratinocytes
The predominant cell type in the epidermis that produces keratin.
Dermal papillae
Small, finger-like projections in the dermis that increase the surface area for better nutrient exchange with the epidermis.
Thick skin
Skin that has five layers of epidermis, found on the palms and soles.
Thin skin
Skin that has four layers of epidermis, covering most of the body.
Acne
A bacterial inflammation of sebaceous glands, often characterized by pimples.
Homeostatic function of skin
Includes protection, temperature regulation, sensation, excretion, and synthesis of vitamin D.