Pediatric Immunizations- NUR 283

How long does Maternal Antibody Protection last?

3-6 months

Why Infants & Young Children Increased Risk for infection?

Decreased inflammatory response, decreased humoral immunity, greater exposure

2 ways to achieve immunity

Natural immunity (infection) & Vaccination

Live Attenuated Vaccines routinely given in US

MMR, Varicella, Rotavirus

Expected vaccine reactions

Redness, swelling, tender at site, low grade fever, fussiness/irritability

When to hold all vaccines?

Moderate to severe illness, high fever, allergic reaction to vaccine components, previous adverse reaction

Adverse vaccine reactions

high fever, seizures, inconsolable crying, severe pain

When to hold love attenuated vaccines?

Immunocompromise: systemic steroid treatment, HIV/AIDS (based on T cell count), cancer, chemo radiation, immunocompromise in close contact or family member, blood or IVIG transfusion, organ transplant

When are live attenuated vaccines administered?

After 12 months

What live attenuated vaccine is given prior to 12 months?

Rotavirus

Why wait to give live attenuated vaccines?

Avoid circulating maternal antibodies